Diabetic Kidney Disease

Part 1 Clinical aspects Chapter 1. Clinical epidemiology of diabetic kidney disease Chapter 2. Long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan Chapter 3. CVD and diabetic kidney disease Chapter 4. Possible biomarkers for diabetic kidney disease Chapter 5. Treatment of Diabetic kidney disease Chapter 6. Future perspectives for treatment of diabetic kidney disease

Part 2. Pathological aspects Chapter 7. Type 1 and 2 diabetes and kidney pathology Chapter 8. Study at AMED collecting 711 biopsy-proven diabetic nephropathy Chapter 9. Evaluation for diabetic kidney lesions Chapter 10. Nephrosclerosis and diabetic kidney diseases Chapter 11. Primary kidney diseases and diabetic kidney disease Chapter 12. Experimental and human diabetic kidney lesions

This book presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of "classic" diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease.Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments.This comprehensive and informative book is an indispensible reference resource for all physicians and researchers in the field of nephrology and diabetes.

Takashi Wada. Kanazawa University. Department of Nephrology and Laboratory. Kanazawa Japan

Kengo Furuichi. Kanazawa Medical University. Department of Nephrology. Kahoku, Ishikawa Japan

Naoki Kashihara. Kawasaki Medical School. Department of Nephrology and Hypertension. Kurashiki. Japan