This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines. As drug discovery for neurodegenerative diseases is one of the largest subspecialties in the field of medicine, the book addresses topics that transcend the borders between disciplines, and presents a wealth of investigations into and discussions on critical questions relevant to the entire field of CNS drug research. It summarizes the available data on the fundamentals of neurotransmitters, treatment of and advanced care for neurodegenerative diseases; and outlines current and future research directions in this field. Combining both conventional and innovative approaches to the topic, the book offers a valuable guide for readers working in medicinal chemistry, the life sciences and allied fields.
Dr. Bijo Mathew, M.Pharm Ph.D., is currently working as an Associate Professor at the Division of Drug Design & Medicinal Chemistry Research Lab, Department of Pharmaceutical Chemistry at Ahalia School of Pharmacy, Palakkad. His areas of interest are: chemistry and biological exploration of various class of chalcones; CNS depressants; anticonvulsant, anticancer, antioxidant, and antitubercular activities, molecular docking, QSAR; and the isolation of natural secondary metabolites from medicinal plants. Dr. Mathew has taught various courses on neurochemistry, organic chemistry and medicinal chemistry. He has published more than 110 papers in journals of national and international repute, one book and 3 book chapters published with the scholarly publishers. He received one patent from Korean Intellectual Property of Office in the topic of composition of preventing or treating of neurological disorders comprising furano chalcone.
Dr. Della Grace Thomas Parambi has 16 years of experience in the field of pharmacy education, and is currently serving as an Assistant Professor at the Faculty of Pharmacy, Jouf University, Saudi Arabia. For the past eight years, her efforts have focused on the development of analytical methods and validation of synthetic, bio and phyto molecules using LC-MS/MS, UPLC, HPTLC, and spectrofluorimetric techniques. She has received several grants from various agencies of the Indian government (Indian Council for Medical Research, Department of Science and Technology, and the Council of Scientific and Industrial Research).