This book offers cutting-edge evidence on using rapid on-site evaluation (ROSE) for the diagnosis of neoplastic diseases in pulmonology. ROSE has become an efficient interventional diagnostics tool and important reference for lung disease differentiation, increasing the adequacy rate, diagnostic yield and accuracy of interventional pulmonary procedures. By performing a rapid stain in the bronchoscopy suite, with evaluation by a trained physician, ROSE can be used to ensure the collection of suitable and sufficient material for ancillary studies in an era of caner-targeted therapy.
ROSE holds considerable value in terms of evaluating sampling adequacy for further immunohistochemistry testing, microbiology studies, flow cytometry analysis, and molecular assays, providing a preliminary diagnosis for patient care. The first part of the book discusses the key principles for performing ROSE procedures and reviews key anatomical structures in the lung. It also covers typical cellular characteristics on the ROSE scale for pulmonary solid malignancies.
The second part of the book features abundant figures and illustrations of ROSE cytopathology in common neoplastic diseases, e.g. adenocarcinoma, squamous-cell carcinoma and small cell lung cancer, while also exploring more unusual types, e.g. pneumonia-type carcinoma of the lung (PTCL), mucinous adenocarcinoma, lung mixed carcinoma, pulmonary metastases from extrapulmonary primary tumors, large cell neuroendocrine carcinoma (LCNEC), and lymphoma.
Jing Feng is a professor and chief at the Division of Pulmonary and Critical Care Medicine and Department of Interventional Pulmonology, Tianjin Medical University General Hospital, Tianjin, China.
Qiang Li is the director of Department of Respiratory Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Hongwu Wang is a professor at the Department of Respiration and Critical Care Medicine, Meitan General Hospital, Beijing.
Faguang Jin is a professor at the Department of Respiration and Critical Care Medicine, Tangdu hospital, the fourth military university.
Hongmei Zhou is a professor at the Department of Respiration and Critical Care Medicine, Affiliated Zhongshan Hospital of Guangdong Medical University.