Hematopathology. Advances in Understanding

Hodgkin's lymphoma revisited.- Hematopoietic stem cell transplant pathology: role of laboratory in transplant.- Acute myeloid leukemia: an update.- Newer complete blood count parameters of clinical significance.- Myeloproliferative neoplasms.- Inhibitors in coagulation.- Histopathology of lymphoreticular system (including both lymph nodes and bone marrow biopsy).- Molecular biology of B & T acute lymphoblastic leukemia.- Complement-mediated hematological disorders.- Genetics of inherited red cell membrane disorders.- Megaloblasticanemia and dual nutrition deficiency.- Inherited disorders of platelet function in relation to hematopoietic transcription factors and their mutations.- Update on testing for von Willebrand disease.- Advances in flow cytometry based paroxysmal nocturnal hemoglobinuria detection.- Role of microRNA in normal and malignant hematopoiesis.- Hepatic coagulopathy: intricacies and challenges.- Iron metabolism and iron deficiency anemia.- Minimal residual disease assessment in myeloma.- Antiphospholipid syndrome.- Alloantigens and their role in immune cytopenia.- Myelodysplastic syndrome 2017.- Prenatal diagnosis of inherited hematological disorders.- Autoimmune myelofibrosis.- Thrombophilia.- Minimal residual disease in acute lymphoblastic leukemia.- RBC membrane disorders.- Lab diagnosis of Microangiopathic hemolytic anemia.- Lab monitoring of anticoagulants.- Next generation sequencing in hematological disorders

This book covers recent advances in the understanding and management of essential hematological pathologies. In addition to updates on Hodgkin's lymphoma, acute myeloid leukemia and other disorders, it provides essential information on transplant pathology, and the molecular and genetic aspects of hematological disorders. Offering a practical approach to lymphoma diagnosis, the book will help hematologists and pathologists alike make accurate diagnoses in keeping with the latest classifications and methodologies. A wealth of photographs and algorithms help readers understand the laboratory approach to the diagnosis of hematological disorders, reflecting the latest advances in the field.

The book offers a valuable resource for residents of MD pathology, DM hematopathology and clinical hematology, as well as practitioners of hematology.

Dr. Renu Saxena is a Professor and head of the Department of Hematology, All India Institutes of Medical Sciences (AIIMS), New Delhi. Her main interests are in the diagnosis and molecular genetics of hemostasis, thrombosis, thalassemia, hemoglobinopathies, hemolytic disorders, and acute and chronic leukemias. DNA analysis for hemophilia A linkage studies, intron 22 and 1 inversion, von Willebrand disease characterization, F V Leiden, prothrombin 20210 and MTHFR gene mutations are some of the areas in which she has been actively involved. Dr Saxena has published more than 350 papers in national and international journals, and is a fellow of the National Academy of Medical Sciences (FNAMS) and International Medical Sciences Academy. In addition, Dr Saxena serves on the editorial boards of numerous national and international journals and on subject expert committees for national scientific bodies like the Indian Council for Medical Research (ICMR), Department of Science and Technology (DST), Council of Scientific and Industrial Research (CSIR), and Department of Biotechnology (DBT). She has been principal investigator for 26 funded research projects, and has received 17 prestigious national and international awards for her contributions in hematology, including the BC Roy Award from the Medical Council of India. Dr. Hara Prasad Pati received his MD pathology from All India Institute of Medical Sciences (AIIMS), New Delhi and subsequently worked as a senior resident/ senior research officer at the Department of Pathology at the same institute. He is currently working as a Professor of Hematology at AIIMS. His research areas include acute leukemia, chronic leukemia (CML), MDS, drug trials (deferiprone), hemostasis, functional platelet disorders, venous thrombosis particularly splanchnic venous thrombosis, red cell enzymology, hemato-poietic cell colony culture, electron microscopy, angiogenesis, immuno-histochemistry and flow cytometry.

Dr Pati has published more than 200 papers in national and international journals and 30 book chapters, and has co-edited six hematology books. Presently, he is editor-in-chief of the Indian Journal of Hematology and Blood Transfusion. Dr Pati is a fellow of the International Medical Sciences Academy, Indian College of Pathologists and Indian Society of Hematology, and a member of the American Society of Hematology and British Society of Hematology.