Natural Compounds as Inducers of Cell Death, Vol. 1

Description

• Multi-disciplinary research fields
• Natural and dietary Products Bioactivity
• Anti-Cancer Research
• Cell Death Mechanisms

The content of this book gives a multi-disciplinary approach into the anti-cancer research field related to natural products and dietary compounds. Mainly, it covers the area of antitumor activity through an in-depth description of the cytotoxic, anti-inflammatory and anti-oxidant properties in cancer, inflammatory and cardio-vascular diseases. The cell death inducing mechanisms (apoptosis, anti-proliferative activity, angiogenesis, cell cycle control, cytostatic property and autophagy) give an overview of how natural products are able to target cancer cells.

Content Level » Research
Keywords » Anti-cancer activity Research - Biochemists - Natural Products Chemists - Phyto-chemistry
Related subjects » Biomedical Sciences

TABLE OF CONTENTS

Section 1, Phytochemicals as inducers of cell death mechanisms.-

• 1. Phytochemicals and Amino Acids: Inducers or Inhibitors of Cell Death?.-
• 2. Pomegranate-derived constituents as inducers of cell death: implications in cancer prevention and therapy.-
• 3. Antitumor effects of anthocyanins: focus on apoptosis.-
• 4. Anti-proliferative and apoptosis-inducing properties of Xanthohumol, a prenylated chalcone from hops (Humulus lupulus L.).-
• 5. Bioavailabitility and Metabolism of Curcuminoids.

Section 2, Natural compounds from animal origins.-

• 6. Melatonin in cell fate decisions: mechanistic perspectives and therapeutical potential.-
• 7. Pharmacologically active compounds from ticks and other arthropods and their potential use in anticancer therapy.

Section 3, Polyphenols as inducers of cell death.-

• 8. Induction of Apoptosis by Polyphenolic Compounds in Cancer Cells.-
• 9. Encapsulation of natural polyphenols with antioxidant properties in polyelectrolyte capsules and nanoparticles.-
• 10. Induction of Cell Death Occurring with Autophagy by Polyphenolic Compounds in Cancer.-

Section 4, Redox active natural compounds.-

• 11. Total antioxidant capacity: a useful tool in assessing antioxidant intake status.-
• 12. Natural sulfur products as redox modulators and selective inducers of cell death.-
• 13. Diallyl sulfides and the decision about life and death of a cell.-

Section 5, Effect of natural compounds on cell cell signaling pathways.-

• 14. Natural compounds as specific inhibitors of cyclin-dependent kinases — past, present and future.-
• 15. Plant-derived isoprenoids mediate regulation of mTOR signaling in tumor cells.-
• 16. Regulation of MicroRNAs by Natural Compounds: Implications for Cancer Therapy.-

Section 6, Phytochemicals in inflammation and cancer.-

• 17. Interference with estrogen receptor-α by dietary components: impact on the balance between cell proliferation and cell death.-
• 18. Natural Triterpenoids from Olive Oil: Potential Activities Against Cancer.-
• 19. Dietary sources of natural inducers of cell death: considerations for cancer therapy and prevention.-

Section 7, Phytochemicals in health and disease.-

• 20. Tocotrienols in the control of pathological fibroinflammatory processes.-
• 21. Anthocyanins: Janus nutraceuticals displaying chemotherapeutic and neuroprotective properties.-
• Index.