Topical Applications and the Mucosa (Current Problems in Dermatology, Vol. 40)

Description

Mucosal membranes have unique anatomical and physiological properties -- differing from those of the keratinized epithelium -- which affect drug or chemical absorption. This makes the diagnosis and treatment of diseases of the mucosa a challenge to dermatologists as well as gynecologists, since many conditions are difficult to recognize and well-established principles of skin disease treatment do not apply to the mucosa.

This volume is exclusively devoted to the mucosal membrane and delivers a better understanding of this distinctive area. Subsequently to introductory chapters on the morphology and physiology of the mucosa, the topical treatment of impaired mucosal membranes is discussed. A third section covers the wide spectrum of consumer products applied on mucosal surfaces. Finally, the safety of products for mucosal membranes is reviewed.

Providing an excellent summary and review of the latest findings and topical applications, this book will be of great value to physicians and clinicians in dermatology or gynecology, pharmacists, scientists and toxicologists who are involved in the development of products for mucosal membranes.

Table of Contents

Section I: Introduction

· Anatomical and Physiological Basis of Topical Therapy of the Mucosa
· Morphology and Physiological Changes of Genital Skin and Mucosa

Section II: Topical Treatment of Impaired Mucosal Membranes

· Nasal Drug Delivery in Humans
· Antimicrobial Topical Agents Used in the Vagina
· Topical Therapy for Mucosal Yeast Infections
· Anti-Inflammatory Treatment
· Topical Antineoplastic Agents in the Treatment of Mucocutaneous Diseases

Section III: Consumer Products and Mucosal Membranes

· Diaper Area and Disposable Diapers
· Products Used on Female Genital Mucosa
· Emollients on the Genital Area
·Oral Care

Section IV: Safety of Products for Mucosal Membranes

· Assessing the Dermal Safety of Products Intended for Genital Mucosal Exposure
· Can the Behind-the-Knee Clinical Test Be Used to Evaluate the Mechanical and Chemical Irritation Potential for Products Intended for Contact with Mucous Membranes?
· Contact Sensitization in the Anal and Genital Area
· Perceptions of Sensitive Skin of the Genital Area
·New Irritation Test Method: Behind the Knee and Mucosa

Further Section

· Author Index
· Subject Index