Causes and consequences of increased adiposity and decreased muscle and bone mass
Increased adiposity and decreased muscle mass contribute substantially to age-dependent
disease and disability. In particular age-related increase in adiposity is quickly
becoming a major threat to public health throughout the world. Although the
hypothesis that age-related changes in body composition are due to lifestyle
choices alone is well accepted, it is a vast oversimplification.
This volume reflects the current knowledge in this rapidly developing field of research. The first part of the book discusses the extent to which increased adiposity contributes to age-related diseases and longevity. The 'obesity paradox', describing the protective role of overweight in decreasing mortality while increasing pathology, is covered in depth. Further chapters address specific aspects of the regulation of energy balance during aging, including the effects of changes in food intake. Finally the causes and consequences of loss of muscle mass and age-related osteoporosis are examined.
A valuable help for physicians treating elderly patients, this book will also be of great interest to researchers studying energy balance, muscle physiology, bone disease, and other aspects of aging.
Title Index Book Series
Non-serial Titles Book News
Contribution of Adipose Tissue to Health Span and Longevity
Huffman, D.M. ; Barzilai, N.
Obesity Paradox during Aging
Central Control of Food Intake in Aging
Changes in Food Intake and Its Relationship to Weight Loss during Advanced Age
McDonald, R.B. ; Ruhe, R.C.
Changes in Body Composition in Response to Challenges during Aging in Rats
New Haystacks Reveal New Needles: Using Caenorhabditis elegans to Identify Novel Targets for Ameliorating Body Composition Changes during Human Aging
Sarcopenia: Prevalence, Mechanisms, and Functional Consequences
Berger, M.J. ; Doherty, T.J.
mTOR Signaling as a Target of Amino Acid Treatment of the Age-Related Sarcopenia
D’Antona, G. ; Nisoli, E.
Mitochondrial Theory of Aging in Human Age-Related Sarcopenia
Parise, G. ; De Lisio, M.
Exercise as a Calorie Restriction Mimetic: Implications for Improving Healthy Aging and Longevity
Clinical, Cellular and Molecular Phenotypes of Aging Bone
Syed, F.A. ; Iqbal, J. ; Peng, Y. ; Sun, L. ; Zaidi, M. ;