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Microbial Host-Interaction: Tolerance versus Allergy, 64th Nestle Nutrition Institute Workshop, Pediatric Program, Sydney, November 2008
Brandtzaeg, P. — Isolauri, E. — Prescott, S.
1ª Edición Agosto 2009
Inglés
288 pags
720 gr
null x null x null cm
ISBN 9783805591676
Editorial KARGER
LIBRO IMPRESO
-5%
196,24 €186,43 €IVA incluido
188,69 €179,26 €IVA no incluido
Recíbelo en un plazo de
2 - 3 semanas
Description
Most indigenous microbes occur in the intestinal tract, and their interactions
with the host are largely unknown. Current understanding of host-microbe interactions
links early microbial contact to the origin of disease, a theory that has its
roots in the hygiene hypothesis. Modern life style appears to deprive the infant
of conditions that provide adequate anti-inflammatory or tolerogenic stimuli
upon antigen encounter. Thus, maturational signals from the environment and
the diet are insufficient to adequately shape the immune system.
This publication deals with the relationship between the gut microbiota as well
as altered pattern of early microbial contact and the origin of human disease.
New aspects of the original hygiene hypothesis are discussed in relation to
disorders spanning from allergy and autoimmunity to obesity. The results presented
suggest that all these disorders may be linked to aberrant antigen absorption
and immune responses associated with dysfunction of mucosal defense.
Researchers, clinicians and students interested in the interaction of the host
with indigenous gut bacteria and the consequences for human health will find
this publication of utmost interest.
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