Metabolism of Human Diseases. Organ Physiology and Pathophysiology

ABOUT THIS BOOK

• First book of this kind describing principles of metabolism in key organs of the human body
• Comprehensive and detailed summary of organ physiological and pathological functioning with focus on biochemical metabolism
• Clearly structured and sorted
• Starts with an overview of the molecular metabolism in a specific organ, describes defective functioning during organ disease and ends with possible treatments and their consequences
• Metabolic pathways involved in common human diseases are highlighted

“Principles of Metabolism in Health and Disease” examines the metabolism of key organs (e.g., pancreas, liver, fat, heart, lung, bone and brain) and how common human diseases, including diabetes mellitus, cirrhosis, metabolic syndrome, asthma, heart failure, stroke, atherosclerosis, hyperlipidemia, hypertonia, cancer, arthritis and neurodegenerative diseases cause defects in metabolism in these organs. Finally, the book describes drugs used to treat these diseases and explains their molecular mechanisms and metabolism. It provides the first summary of the metabolism of individual organs and their physiological and pathological functioning. “Principles of Metabolism” is a musthave, stateoftheart work written for graduate students, post docs and professors in biochemistry, physiology and medicine, as well as for physicians treating organ diseases.

Content Level » Graduate
Keywords » key organs lipid metabolism metabolic diseases
Related subjects » Biochemistry & Biophysics Human Physiology Internal Medicine

TABLE OF CONTENTS

1. Gastrointestinal tract.
   Overview. Lactose intolerance. Colon carcinoma. Peptic ulcer. Gastroenteritis.
2. Pancreas.
   Overview. Diabetes mellitus.
3. Liver.
   Overview. Cirrhosis.
4. Fat tissue.
   Overview. Metabolic syndrome.
5. Lung.
   Overview. Asthma. COPD. Lung cancer. Pneumonia.
6. Heart.
   Overview. Coronary artery disease. Heart failure.
7. Blood vessels.
   Overview. Stroke. Arteriosclerosis. Varicose veins.
8. Blood.
   Overview. Sickle cell disease. Hyperlipidemia.
9. Kidney.
   Overview. Renal failure. Gout and hyperuricemia. Kidney stones. Urinary tract infection. Hypertonia.
10. Thyroid gland.
    Overview. Goiter.
11. Reproductive system.
    Overview. Breast/prostate cancer. Down syndrome.
12. Immune system.
    Overview. Sepsis. Fever. Allergies.
13. Upper respiratory tract.
    Overview. Common cold.
14. Eye.
    Overview. Macular degeneration. Glaucoma.
15. Brain.
    Overview. Epilepsy. Major depressive disorder. Parkinson’s disease. Alzheimer’s disease. Clusterheadache and migraine. Schizophrenia.
16. Peripheral nervous system.
    Overview. Multiple sclerosis. Carpal tunnel syndrome.
17. Joints.
    Overview. Osteoarthritis. Rheumatoid arthritis.
18. Teeth and bones.
    Overview. Dental caries. Osteoporosis.

AUTHORS & EDITORS

Professor Eckhard Lammert, PhD. Studies of Biochemistry and Molecular Biology at the University of Hamburg, Germany. In 1995 Master thesis at the German Cancer Research Center (DKFZ), University of Heidelberg. In 1998 PhD at the Eberhard –Karls –University of Tübingen, Germany. Four year postdoctoral research at the Harvard University in Cambridge, MA, USA. From 2002 to 2008 Research Group Leader at the MaxPlanck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. Since 2008 Full Professor and Head at the Institute of Metabolic Physiology at the HeinrichHeineUniversity in Düsseldorf, Germany. Research Interests: blood vessel formation, onset of type II diabetes mellitus in connection with vascular changes; cellcell interactions in pancreatic islets, insulin secretion. For his work on type II diabetes mellitus Eckhard Lammert received the PaulEhrlichundLudwigDarmstaedterYoungInvestigatorAward in 2008.