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Pancreatology. From Bench to Bedside
Iovanna, J. — Ismailov, U.
1ª Edición Agosto 2009
Inglés
Tapa blanda
92 pags
1000 gr
16 x 24 x 1 cm
ISBN 9783642001512
Editorial SPRINGER
LIBRO IMPRESO
-5%
51,99 €49,39 €IVA incluido
49,99 €47,49 €IVA no incluido
Recíbelo en un plazo de
2 - 3 semanas
'Pancreatology: from Bench to Bedside' focusses on recent advances in pancreatic basic research, genetics of the pancreatic diseases and its surgical management.
Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets. Also, very original results show the unexpected role of lipids as mediators during acute pancreatitis. Gene screening strategies allow the detection of the genes responsbile for gemcitabine resistance of pancreatic cancer cells . They lead to the selection of several target genes, in order to suppress the resistance of cells to gemcitabine treatment. The mechanism by which tetrahydrocannabinol is anti-tumoral in pancreatic cancer cells is presented and the use of THC as a promising new therapeutic agent is discussed.
Genetic data are shown concerning hundreds of families with hereditary chronic pancreatitis and their possible role in the pathogenesis of the disease. Another very original study addresses the prevention and treatment of pancreatic diseases with diat.
In clinical research, convincing data about the use of endoscopic sphicterotomy in the management of acute bilary pancreatitis is presented, based on the experience of a Center highly specialized in pancreatic diseases.
Written for: Specialists of all levels working in the field of pancreatology
Keywords:
- Basic research
- Clinical
- Genetics
- Necrosis
- Pancreas
Table of contents
Heat Shock Proteins in Pancreatic Diseases.- Cellular Stress in Acute Pancreatitis.-
Systemic Inflammatory Effects of Acute Pancreatitis: Effects of Lipid Mediators.-
Gemcitabine Changes the Gene Expression in Human Pancreatic Cancer Cells: Search
for New Therapeutic Molecular Targets.- Cannabinoids as Potential Antitumoral
Agents in Pancreatic Cancer.- Pathogenesis of Chronic Pancreatitis with Special
Emphasis on Genes.- Bioecological Control of Disease, Especially Pancreatic
Disease.- The Role of Endoscopic Sphincterotomy in the Management of Acute Biliary
Pancreatitis.- Indication for Surgery in Acute Necrotizing Pancreatitis.- Index.
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