Doping in Sports

About this book

Doping in sports and the fight against it has gained increasing attention in recent years. The pharmacological basis for a possible performance enhancement in competitive sport through the administration of prohibited substances and methods as well as the analytical disclosure of such practices are comprehensively covered in 21 contributions by outstanding and distinctive authors.

Written for: Libraries; scientists and researchers in the fields of pharmacology and sports medicine

Keywords:

Anti-Doping
Doping Analysis
Drug Metabolism
Prohibited Substances
Sport Performance

Table of contents

Preface.- History of Doping and Doping Control. Biochemical and Physiological Aspects of Endogenous Androgens. Phase-II-metabolism of androgens and its relevancy for doping control analysis. Detecting the administration of endogenous anabolic androgenic steroids. Synthetic Anabolic Agents – Steroids and Non-Steroidal Selective Androgen Receptor Modulators. Nandrolone – a multi-faceted doping agent. Designer steroids. Growth hormone. Mass Spectrometry-based analysis of IGF-1 and hGH. Insulin. Beta-adrenergic stimulation. Erythropoietin and analogues. The athlete's biological passport and indirect markers of blood doping. Masking and manipulation. Hormonal growth promoting agents in food producing animals. Some Aspects of Doping and Medication Control in Equine Sports. Androgenic-anabolic steroid abuse and the cardiovascular system. Pathological findings and structure-activity-relationships. Gene doping. Science and the Rules Governing Anti-Doping Violations.