A Guide to Bone Marrow Transplantation

H.J. Deeg , University of Washington School of Medicine,Seattle, WA, USA
H.-G. Klingemann , Chicago, IL, USA
G.L. Phillips , University of Kentucky, Lexington, KY, USA
G.V. Zant , University of Kentucky, Lexington, KY, USA

This completely revised and enlarged 3rd edition continues the idea of the previous version to provide an up-to-date overview of blood and marrow transplantations. Indication to transplantation and pre-transplant considerations are discussed in detail before the transplant procedure with all acute and delayed procedure is described. An outlook on the latest developments and their future aspects is included, and problems and pre- and post-transplant complications are discussed. This book helps practising hematologists, oncologists,and other physicians as well as physicians in training and students to develop an idea as to when blood and marrow transplantation should be considered, what the costs are and how a donor can be selected.

H.J. Deeg , University of Washington School of Medicine,Seattle, WA, USA
H.-G. Klingemann , Chicago, IL, USA
G.L. Phillips , University of Kentucky, Lexington, KY, USA
G.V. Zant , University of Kentucky, Lexington, KY, USA

Contents: Introduction.- Pretransplant Considerations. Rationale and Indications for Transplantations.Timing of Transplantation. Stem Cell Sources. Preparation for Stem Cell Transplantation. Cost Considerations.- Transplant Procedure.Conditioning Regimens. Collection and Processing of Stem Cells. In Vitro Expansion of Stem Cells. Genetic Manipulation of Hematopoietic Stem Cells. Prevention and Treatment of Relapse.- Transplant-Related Problems.- Side Effects of Conditioning Regimens. Graft Failure. Graft-Versus-Host Disease. Management of Infections. Single and Multi- Organ Failure. Chronic Graft-Versus-Host Disease. Delayed Complications.- Long-Term Observations. Follow-Up After Discharge from the Transplant Center. Rehabilitation.- Quo Vadis