M.
Molls, Technical
University Munich, Germany; P. Vaupel, University of Mainz, Germany
(Eds.)
(Medical Radiology. Diagnostic Imaging
and Radiation Oncology. Eds.:A.L. Baert, L.W. Brady, H.-P.
Heilmann, F.H.W. Heuck, J.E. Youker)
This book summarizes current
knowledge on blood perfusion and the microenvironment of human
tumors, enabling the reader to gain a deeper insight into the
physiological components of malignant tumors. Among a range of
topics, detailed consideration is given to circulatory parameters,
including blood and nutrient supply, transvascular and interstitial
transport, and oxygenation, as well as to bioenergetic status and the
influence of pH on the responsiveness of malignant tumors to
nonsurgical treatments such as radiotherapy and chemotherapy. For the
clinician, it will be of special interest to read about the various
invasive and noninvasive methods (including MR and PET) that allow
the tumor physiology and microenvironment of an individual patient to
be characterized.
