Breast Cancer. Nuclear Medicine in Diagnosis and Therapeutic Options

About this book

• Brings up-to-date nuclear medical knowledge in breast cancer
• Includes vital information on advances in the field of diagnosis
• Supplies data on the development of some new modalities
• Offers a general overview of the available tools for breast cancer treatment

There can never be enough material in the public domain about cancers, and particularly breast cancer.

This book adds much to the literature. It provides general information on breast cancer management and considers all new methods of diagnosis and therapy.

It focuses on nuclear medicine modalities by comparing their results with other diagnostic and therapeutic approaches.

The coverage provides readers with up-to-date knowledge on breast cancer as well as information on the advances in the field of diagnosis.

It also details data on the development of some new modalities and provides a general overview of the available tools for breast cancer treatment.

In sum, it is a hugely useful text that performs a dual function. Not only does it provide practitioners of all descriptions with a vital overview of the current state of play in breast cancer treatment, but it also lays out in a beautifully structured way the latest diagnostic methodologies.

Written for: Gynecologists, radiologists, oncologists, surgeons

Keywords:

• Breast Cancer Diagnosis and Management
• Nuclear Medicine Imaging
• Nuclear Medicine Therapy
• Nuclear Medicine in Breast Cancer
• Position of Nuclea Medicine in Breast Cancer Treatmen

Contents

1 Introduction
2 Histological Classifi cation of Breast Cancer
Alessandra Fabbri, Maria Luisa Carcangiu, and Antonino Carbone
3 Biomarkers for Breast Cancer: Towards the Proposition of Clinically Relevant Tools
Maria Grazia Daidone, Vera Cappelletti, Angelo Paradiso, Massimo Gion, Nadia Harbeck, Fred Sweep, and Manfred Schmitt
4 Circulating Tumour Markers in Breast Cancer
Ettore Seregni, Antonio Coli, and Nicola Mazzuca
5 Axillary Lymph Node Status Evaluation in Breast Cancer Patients:
Role of SPECT and Pinhole SPECT with Cationic Lipophilic Radiotracers
Giuseppe Madeddu and Angela Spanu
6 Breast Imaging with Scintimammography
Orazio Schillaci and John R. Buscombe
7 99mTc-MIBI in the Evaluation of Breast Cancer Biology
Silvana Del Vecchio, Antonella Zannetti, Rosa Fonti, Francesca Iommelli, and Marco Salvatore
8 Sentinel Node Detection in Pre-Operative Axillary Staging
Giovanni Paganelli, Giuseppe Trifi rò, Oreste Gentilini, Mattia Intra, Giuseppe Viale, and Umberto Veronesi
9 State of the Art of Current Modalities for the Diagnosis of Breast Lesions
Cosimo Di Maggio
10 New Trends of MRI in Breast Cancer Diagnosis
Daniele Vergnaghi, Giovanna Trecate, and Siranoush Manoukian
11 PET Imaging of Breast Cancer Molecular Biomarkers
Elisabetta Brugola, Andreas K. Buck, Lucia Tagliabue, Sven N. Reske, and Giovanni Lucignani
12 The Role of FDG-PET for Axillary Lymph Node Staging in Primary Breast Cancer
Flavio Crippa, Alberto Gerali, Alessandra Alessi, Roberto Agresti, and Emilio Bombardieri
13 Measuring Response to Chemotherapy in Locally Advanced Breast Cancer: Methodological Considerations
Nanda C. Krak, Otto S. Hoekstra, and Adriaan A. Lammertsma
14 FDG-PET in Monitoring Therapy of Breast Cancer
Hans-Jürgen Biersack, Hans Bender, and Holger Palmedo
15 FDG-PET and Tumour Marker Tests for the Diagnosis of Breast Cancer
Emilio Bombardieri, Alessandra Alessi, Federica Pallotti, Gianluca Serafi ni, Nicola Mazzuca, Ettore Seregni, and Flavio Crippa
16 Advantages and Limitations of FDG PET in the Follow-Up of Breast Cancer
Peter Lind, Isabel Igerc, Thomas Beyer, Abdul Jalil Nordin, Peter Reinprecht, and Klaus Hausegger
17 PET/CT and Breast Cancer
Maria Picchio, Cristina Messa, Barbara Zangheri, Claudio Landoni, Lugio Gianolli, and Ferruccio Fazio
18 Current Role of Bone Scan with Phosphonates in the Follow-Up of Breast Cancer
Lorenzo Maffi oli, Luigia Florimonte, Luca Pagani, Ivana Butti, and Isabel Roca
19 Progress in the Treatment of Early and Advanced Breast Cancer
Valentina Guarneri, Frederico Piacentini, and PierFranco Conte
20 186Re-HEDP for Metastatic Bone Pain in Breast Cancer Patients
Marnix G. E. H. Lam, John M. H. de Klerk, and Peter P. van Rijk
21 153Sm-EDTM for Bone Pain Treatment in Skeletal Metastases
Carlo Ludovico Maini, Serenella Bergomi, Rosella Pasqualoni, Lidia Strigari, and Rosa Sciuto
22 The Choice of the Correct Imaging Modality in Breast Cancer Management
Paola Mariani and Luca Gianni
Subject Index

Reviews

"This book provides a complete overview of the diagnostic and therapeutic aspects of nuclear medicine in breast cancer. … The audience includes nuclear medicine professions, radiologists, oncologists, and residents and fellows in those fields. This book is a valuable aid for new practitioners as well as experienced nuclear medicine physicians who are called upon for treatment of breast cancer. … This excellent book will be a great addition to any nuclear medicine physician’s library … ." (Oussama Nachar, Doody's Review Service, February, 2008)