Diagnosis of Endometrial Biopsies and Curettings. A Practical Approach

Introduction.- The Normal Endometrium.- Pregnancy, Abortion, and Ectopic Pregnancy.- Gestational Trophoblastic Disease.- Abnormal Uterine Bleeding: Non-Structural Causes.- Effects of Hormones.- Endometritis.- Polyps.- Precursors of Endometrial Carcinoma.- Endometrial Carcinoma.- Mesenchymal Tumors and Other Rare Neoplasms.- Methods of Endometrial Evaluation.

The third edition of this text entails a comprehensive review of pathophysiology, including the recognition of physiologic conditions andpathologic entities, such as polyps, endometritis, gestational trophoblastic diseases, endometrial hyperplasia, and carcinoma. It alsoserves as an update on the use of current terminology and ancillary tools. Th e authors incorporate signifi cant updates related to theexpansion of their knowledge of old and newer entities and the use of immunohistochemical and molecular ancillary techniques to assist inaccurately diagnosing endometrial biopsies. Th e chapters also include recommendations and suggestions of appropriate terminology for apathology report, as well as specifi c pitfalls, mimickers and confounding factors in the diagnosis of endometrial samples, such as surfacemetaplasias, cytoplasmic changes, and endocervical contaminants. The complicated subject of hyperplasia and cancer precursors is discussedat length with an expanded commentary on the application of the term endometrioid intraepithelial neoplasia (EIN) and how itrelates to the traditional classifi cation of endometrial hyperplasia. Additionally, a substantial number of new, richly colored imageshelps readers fully understand and confi dently classify such complex specimens.

The newest edition of Diagnosis of Endometrial Biopsies and Curettings serves as a useful resource not only for pathologists in trainingand practicing pathologists, but also to experienced physicians, other health care providers and researchers that deal with and are interestedin endometrial pathology.

Tricia A. Murdock, MD. The Johns Hopkins Hospital Baltimore, MD, USA
Emanuela F.T. Veras, MD. The Johns Hopkins Hospital Baltimore, MD, USA
Robert J. Kurman, MD. The Johns Hopkins Hospital Baltimore, MD, USA
Michael T. Mazur, MD SUNY Upstate Medical University Syracuse, NY, USA