This volume provides a concise yet comprehensive overview of precancerous lesions and gynecologic tract cancers. Each section discusses the historic evolution of a precancerous lesion, its epidemiology, the nature of the published evidence that supports its characterization as a precancerous lesion, and gives a detailed description of morphologic, immunophenotypic and molecular properties, and patient outcomes. The volume also features 2 separate chapters on the clinical management of precancerous lesions of the gynecologic tract as a well as the cytopathology of cervical precancerous lesions. Lavishly illustrated and written by some of the foremost experts in the field, Precancerous Lesions of the Gynecologic Tract: Diagnostic and Molecular Genetic Pathology is a definitive account of precancerous lesions of the gynecologic tract and is a valuable resource for pathologists, oncologists, and gynecologists.
Section I: Ovary, Fallopian Tube and Peritoneum 1. Precursors of High Grade Serous Carcinoma Patricia A. Shaw, Blaise Clarke, Sophia HL George 2. Precursors of Low Grade Serous Adenocarcinoma of the Ovary: Pathology and Molecular Pathways Kate Lawrenson, Paulette Mhawech-Fauceglia 3. Precancerous lesions of ovarian clear cell and endometrioid carcinomas Andres A. Roma 4. Clinical Management of Selected Precancerous Lesions of the Uterus, Fallopian Tube, and Ovary Xiaomang B. Stickles Section II: Uterine Corpus 5. Precancerous Lesions of the Gynecologic Tract: Diagnostic and Molecular Genetic Pathology Natalia Buza and Pei Hui 6. Putative precursors of Uterine Sarcomas Qing Zhang, Jian-Jun Wei 7. Precancerous Lesions of Endometrioid Adenocarcinoma Susanne K. Jeffus, Charles M. Quick 8. Precancerous lesions of endometrial serous carcinomas Oluwole Fadare, Wenxin Zheng Section III: Uterine Cervix, Vulva and Vagina 9. Vulvar Intrapithelial Neoplasia Demaretta S. Rush, Edward J. Wilkinson 10. Vaginal Intraepithelial Neoplasia Philip P.C. Ip, Ka Yu TSE 11. Cytology of Cervical Precancerous Lesions Zaibo Li, Chengquan Zhao 12. Precursors of Cervical Adenocarcinomas Yoshiki Mikami, Atsumi Kojima 13. Precancerous lesions of squamous cell carcinoma of the cervix: squamous dysplasia Lynn Hirschowitz, Simon Herrington 14. Clinical managemen t of precancerous lesions in the lower genital tract Hironori Tashiro, Hidetaka Katabuchi