No hay productos en el carrito



Familial Mediterranean Fever
Gattorno, M.
1ª Edición Marzo 2015
Inglés
Tapa dura
162 pags
200 gr
18 x 24 x null cm
ISBN 9783319146140
Editorial SPRINGER
LIBRO IMPRESO
-5%
114,39 €108,67 €IVA incluido
109,99 €104,49 €IVA no incluido
Recíbelo en un plazo de
2 - 3 semanas
Description
This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic autoinflammatory disease. The opening chapters explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies. A large part of the book is then devoted to a detailed description of the typical and atypical clinical presentations, the disease course, and potential complications in both pediatric and adult patients. Guidance is provided on the measurement of disease severity and the management of patients in daily practice. The advice regarding treatment is based on the best currently available evidence and attention is also paid to important emerging treatments.
The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Monogenic autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Familial Mediterranean fever itself is due to a mutation in theMEFVgene, which codes for the protein pyrin; it is characterized by periodic fever and episodes of painful inflammation in the abdomen, chest, and joints. Familial Mediterranean Fever will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with the disease.
Contents
Preface.- 1 Genetics.-2 Pathogenesis.-3 Clinical Picture in Childhood.- 4 Clinical Picture in Adulthood and Unusual Clinical Features.-5 FMF in Western Countries.-6 Long Term Complications in FMF.- 7 Recent advances in quantitative assessment of FMF.- 8 How to Manage FMF Patients in Daily Practice.- 9 New Emerging Treatments.-Subject Index.
© 2025 Axón Librería S.L.
2.149.0