Laboratory Hemostasis. a Practical Guide for Pathologists

Descripcion

Coagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anti-coagulant monitoring and management. This handbook will provide practical information and guidance on the topics relevant to directing a coagulation laboratory and be of interest to pathologists, clinical laboratory scientists, residents, fellows, as well as coagulation laboratory supervisors, technologists and technicians.

Table of Contents

Preface
Acknowledgments
Role and Responsibilities of the Laboratory Director Sterling T. Bennett 1
Collection of Coagulation Specimens Sterling T. Bennett 27
Instrumentation for the Coagulation Laboratory Christopher M. Lehman Catherine Thompson 41
Validation of Coagulation Assays, Instruments and Reagents Sterling T. Bennett 57
Hemostasis Screening Assays George M. Rodgers Christopher M. Lehman 85
Testing for Inherited Bleeding Disorders George M. Rodgers 103
Testing for Acquired Platelet Disorders Christopher M. Lehman 121
Acquired Coagulation Disorders and TTP George M. Rodgers 137
Testing for Inherited and Acquired Thrombotic Disorders George M. Rodgers 143
Monitoring Anticoagulant Therapy Sterling T. Bennett 167
Coagulation Testing and Transfusion Medicine Robert C. Blaylock Christopher M. Lehman 207
Index 227

Authors

Sterling T. Bennett, M.D., M.S., is the Medical Director, Intermountain Healthcare Central Laboratory, and Volunteer Adjunct Associate Professor of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah

Christopher M. Lehman, M.D., is an Associate Professor of Pathology, University of Utah Health Sciences Center and the Assistant Director of Hospital Laboratories, ARUP Laboratories, Salt Lake City, Utah

George M. Rodgers, M.D., Ph.D., is a Professor of Medicine and Pathology in the Division of Hematology, University of Utah Health Sciences Center, and the Medical Director of the Coagulation Laboratory at ARUP Laboratories, Salt Lake City, Utah