The Handbook of Juvenile Idiopathic Arthritis is an in-depth and comprehensive guide for the treatment and management of patients with this condition. The Handbook provides an informative review of the disease looking at the epidemiology, etiology and pathogenesis, issues of diagnosis and classification, consequences and complications, general treatment aspects, as well as both non pharmacologic and pharmacologic therapy whilst considering the future outlook for patients with juvenile idiopathic arthritis. Juvenile idiopathic arthritis is the most common type of arthritis found in children and adolescents affecting about 1 in 1,000 children. It is a chronic disease which causes inflammation, pain and swelling of the affected joints and can affect joints in any part of the body. This Handbook provides an unbiased, informative discussion of the current and emerging treatments in this field.
- Reviews current treatment recommendations for juvenile idiopathic arthritis based on the latest guidelines and clinical trials
- Easily accessible text offers a practical and informative clinical resource for busy health care professionals
- Written by a world-renowned expert in juvenile idiopathic arthritis
Chapter 1 – Introduction (Disease overview; Epidemiology; Prognosis)
Chapter 2 – Etiology and pathogenesis (Genetic susceptibility; environmental triggers; role of humoral and cell-mediated immunity in JIA pathogenesis; causes and pathogenesis of systemic disease)
Chapter 3 – Diagnosis and classification (Clinical manifestations of JIA; the ACR, EULAR, and ILAR criteria for classification of JIA; subtypes of JIA; challenges in classifying JIA; diagnosis of JIA)
Chapter 4 – Consequences and complications of JIA (Disease course of different subtypes; skeletal abnormalities, abnormalities of growth, ophthalmologic complications; complications of systemic arthritis; health-related quality of life and JIA)
Chapter 5 – General treatment aspects (Goals of treatment; measuring treatment response, treatment guidelines, a multidisciplinary approach to JIA treatment; special considerations in the pediatric patient)
Chapter 6 – Nonpharmacologic therapy (Psychosocial factors, including counselling for patients and parents; school performance, such as academic counseling, school-life adjustments, and physical education adjustments; nutrition; physical therapy)
Chapter 7 – Pharmacologic therapy (Nonsteroidal anti-inflammatory drugs; corticosteroids (oral and intra-articular steroid injections); disease modifying anti-rheumatic drugs (DMARDS); biologic therapy)
Chapter 8 – Conclusions and future outlook
Angelo Ravelli is Associate Professor of Pediatrics at the School of Medicine of the University of Genoa, Italy, a position held since 2006. He is Chief of the Centre of Clinimetrics of the Istituto Giannina Gaslini of Genoa, Italy, a position he has held since 2012. Previously, he was Chief of the Interventional Rheumatology Unit at the same institution. After completion of a degree in medicine, Dr Ravelli specialized in paediatrics and allergology. His field of clinical and research activity focuses on paediatric rheumatology.
Dr Ravelli has been invited to speak in more than 200 national and international meetings and has published more than 220 full-length articles in international scientific journals, with a total impact factor of more than 1,200 and an h-index of 43. He has received numerous grants and awards, including the Gerolamo Prize for Excellence in Research in 2004. He is Associate Editor of Pediatric Rheumatology Online Journal, Assistant Editor of Clinical and Experimental Rheumatology and serves on the Editorial Board of The Journal of Rheumatology and Arthritis Care & Research. He is a member of the Executive Committee of the European Rheumatology Research Foundation and was Chairman of the Lupus Working Group of the Pediatric Rheumatology European Society (PReS) from 2004 to 2010.