


Cancer and Aging. from Bench to Clinics (Interdisciplinary Topics in Gerontology, Vol. 38)
Extermann, M.
ISBN-13: 9783318023060
KARGER
Febrero / 2013
1ª Edición
Inglés
Tapa dura
170 pags
1000 gr
x x cm
Recíbelo en un plazo De 2 a 3 semanas
Description
Outlining the complex interaction between the two phenomena
Cancer is clearly an age-related disease. Recent research in both aging and
cancer has demonstrated the complex interaction between the two phenomena. This
affects a wide spectrum of research and practice, anywhere from basic research
to health care organization.
Core examples of these close associations are addressed in this book. Starting
with basic research, the first chapters cover cancer development, mTOR inhibition,
senescent cells altering the tumor microenvironment, and immune senescence affecting
cancer vaccine response. Taking into account the multidisciplinarity of geriatric
oncology, several chapters focus on geriatric and oncologic aspects in patient
assessment, treatment options, nursing and exercise programs. The book is rounded
off by a discussion on the impact of the metabolic syndrome illustrating the
interactions between comorbidity and cancer and a chapter on frailty.
This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.
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