ABOUT THIS BOOK
Technological advances, together with a better understanding of the molecular
biology of infectious microorganisms, are creating exciting possibilities for
a new generation of replicating vaccines. Historically, live vaccines have been
either directly derived from a natural source or attenuated by empirical approaches
using serial passages and host cell adaptation. Currently, we are witnessing
a quantum leap in our technological capabilities to specifically modify the
genetic make-up of viruses and bacteria, making it possible to generate improved
live vaccines and to develop completely new types of replicating vaccines, such
as vectored vaccines, single-round infectious vaccines and replicon vaccines.
This book highlights some of the most exciting recent developments towards a
new generation of replicating vaccines.
Content Level » Research
Related subjects » Immunology - Medical Microbiology - Virology