Non-Neoplastic Cytology. A Comprehensive Guide

Cytology Specimen Collection, Preparation, and Stains.- Urinary Tract Cytology.- Cervical and Vaginal Cytology.- Peritoneal Washing and Ovary.- Body Cavity Fluid Cytology.- Salivary Gland.- Thyroid Gland.- Neck Lesions.- Lymph Node.- Breast.- Respiratory Tract.- Gastrointestinal Tract.- Pancreas.- Liver and Biliary Tract.- Kidney and Adrenal Gland.- Soft Tissue.- Bone.- Brain and Cerebrospinal Fluid.- Quick Review.

Cytology evaluates cellular details, and in contrast, histology relates to tissue assessment with rather preserved architecture. During daily cytology practice, we frequently encounter certain situations which are often challenging such as differentiating normal cytology components or non-neoplastic lesions from a neoplastic process, abnormality versus artifact, contaminants from lesional sampling, immunostain expression in unexpected cells, identifying/or characterizing infectious microorganisms and use of special stains. In-depth knowledge about normal tissue cytology, the pattern of immunohistochemical expression in various organs, and recognizing diagnostic pitfalls would help to overcome diagnostically challenging situations.

This book presents a detailed and state-of-the-art approach to non-neoplastic cytology. High-yield content, mostly used in daily practice, is in tabular format. The book provides detailed information about cytomorphologic features of infectious microorganisms and the use of special stains, the use of immunohistochemistry along with expression in normal cell types, artifacts/contaminants or incidental findings, and cytomorphologic features of non-tumor related lesions in an organ-based structure. There is a further elaboration of differential diagnosis and mimickers of cytologic material from normal parenchymal tissue, infectious/inflammatory conditions, and benign cystic lesions. The last chapter describes a quick overview of important reference material in tables, which is useful for daily anatomic pathology sign-out. Non-Neoplastic Cytology: A Comprehensive Guide provides practical information about non-neoplastic cytology in one concise format using tables and images. It aims to be a practical resource for cytotechnologists, pathologists, pathology residents, and fellows.

Syed M. Gilani, MD - Department of Pathology, Albany Medical Center, Albany Medical College
Albany, New York, USA

Guoping Cai, MD - Department of Pathology, Yale School of Medicine, New Haven, CT, USA