Heart Valves. From Design to Clinical Implantation

Part I. Anatomy, Physiology, Congenital Defects, and Disease
1. The Anatomy and Function of the Atrioventricular Valves
2. The Anatomy and Function of the Semilunar Valves
3. Congenital Heart Defects Which Include Cardiac Valve Abnormalities
Part II. Valve Repair and Replacement
4. Heart Valve Disease
5. History of Heart Valve Repair
6. The Ross Procedure
7. Echocardiographic Imaging of Cardiac Valves
8. Advanced 3D Imaging and Transcatheter Valve Repair/Implantation
9. Transcatheter Mitral Repair and Replacement
10. Percutaneous Pulmonary Valve Implantation: 20 Years of Development
11. Transcatheter Aortic Valve Implantation
12. Post-TAVI PCI
13. Tissue-Engineered Heart Valves
14. Anticoagulation Management for Mechanical Valves in the On-X Era
Part III. Testing, Regulatory and Training Issues
15. In Vitro Testing of Heart Valve Substitutes
16. Perspectives on Heart Valve Modelling: Contexts of Use, Risk, Validation, Verification and Uncertainty Quantification and End-to-End Example
17. Numerical Methods for Design and Evaluation of Prosthetic Heart Valves
18. Animal Models for Cardiac Valve Research
19. The Preclinical Uses of Isolated Heart Models and Anatomic Specimens as Means to Enhance the Design and Testing of Cardiac Valve Therapies
20. Clinical Trial Requirements for Cardiac Valves
21. Clinical Applications of 3D Modeling and Printing for Intracardiac Valves
22. Procedural Training and Education: A Multimodal and Interactive Approach

This state-of-the-art handbook is dedicated to cardiac valve anatomy, models for testing and research methods, clinical trials; and clinical needs and applications. In this new edition, chapters are updated with the latest research in addition to new chapters on complex repair of CHD requiring conduits, new trends for valve replacement like the Ozaki procedure, as well as complex procedures in TAV, SAV, HARPOON, and BASILICA, with case studies for each type of procedure. This volume serves as a helpful reference for patients, educators, students, device designers and developers, clinical study specialists, clinicians, and other associated healthcare providers.