Mechanical Ventilation from Pathophysiology to Clinical Evidence

Part 1.

 

Techniques

Chapter 1. Basic physiology of respiratory system: gas exchange and respiratory mechanics Chapter 2. A short history of Mechanical Ventilation

Chapter 3. Airway management in critically ill

Chapter 4. Controlled mechanical ventilation: modes and monitoring

Chapter 5. Assisted ventilation: pressure support and bilevel ventilation modes

Chapter 6. Monitoring the patient during assisted ventilation

Chapter 7. Neurally Adjusted Ventilatory Assist

Chapter 8. roportional Assist Ventilation

Chapter 9. Non-invasive ventilation: indications and caveats

Chapter 10. High-flow Nasal Cannula

Chapter 11. Nursing of mechanically ventilated and ECMO patient

Chapter 12. Closed Loop ventilation modes

Chapter 13. Aiway pressure release ventilation

 

 

Part 2.

 

Clinical Scearios

Chapter 14. Acute Respiratory Failure and Acute Respiratory Distress Syndrome

Chapter 15. Ventilator Induced Lung Injury and Lung Protective Ventilation

Chapter 16. Mechanical ventilation in the heathy lung: OR and ICU

Chapter 17. PEEP setting in ARDS

Chapter 18. Ventilation in brain injured patient

Chapter 19. Invaisve and noninvasive ventilation in patient with cardiac failure

Chapter 20. COPD and severe asthma

Chapter 21. Ventilation in the obese patient

Chapter 22. Weaning the simple and complex patients

Chapter 23. Noninvasive ventilation in COVID-19

Chapter 24. Invasive Ventilation in COVID-19

Chapter 25. Mechanical ventilation in different surgical settings

Chapter 26. Following up the patients at long term

Chapter 27. Mechanical Ventilation in limited resource settings

Chapter 28. Mechanical Ventilation during patient's trasferral

 

 

Part 3.

 

Adjuncts to MV

Chapter 29. Prone Position

Chapter 30. Veno-Venous ECMO and ECCO2R

Chapter 31. Mechanical Ventilation setting during ECMO

 

Part 4.

 

Monitoring

Chapter 32. Ultrasound assesment of the respiratory system

Chapter 33. Electrical Impedance Tomography

Chapter 34. Esophageal pressure monitoring

Chapter 35. Lung Volumes and volumetric capnography

Chapter 36. Radiological monitoring

Chapter 37. Clinical vignettes (waveforms)

Chapter 38. Teaching Mechanical ventilation: on line resources and simulation

This book aims to give a comprehensive overview of the current challenges and solution posed to the health care professionals who need to use mechanical ventilation to treat their patients.
Mechanical ventilation is a cornerstone of the treatment of critically ill patients, as also dramatically underlined by the recent COVID-19 pandemic. The topic is not simple to approach, since it requires integration of multiple data which, in turn, result from complex interplays between patient’s condition and ventilatory settings. While technological development empowered advanced monitoring and decision support, these also increase the burden of data on the practitioners.

 

Furthermore, considering that sometimes mechanical ventilation is seen under two, apparently opposite, approaches, “physiology vs. protocols”, the book aims to reconcile these two aspects. And this has been done by each author following the above trajectory in their chapters.

 

The exposure of the topic begins from the “pathophysiology” (i.e. the “physiology of the disease”) so that the reader can better understand the concept and rationale of any given approach. At the same time, any rationale or hypothesis (for as much as supported by physiology) must hold at the proof of clinical research and evidence, which is summarized in each chapter.

 

In summary, the purposes is that the readers understand not only which is the best clinical practice to adopt but also why and which mechanisms this is based upon and how to approach a novel issue they might encounter. The book – addressed to physicians, nurses and respiratory therapist – features chapters on “novel” or “hot” topics like, obviously, COVID-19, ECMO, but also MV in low resource setting.

 

 

Contributor Bio(s)

Dr. Giacomo Bellani is Associate Professor of Anesthesia and Critical Care Medicine of the University of Milan-Bicocca, in Monza, Italy and staff physician in the general Intensive Care Unit of San Gerardo Hospital, where he completed the postgraduate training program in Anesthesia and Critical Care. In 2003-2004 he was research fellow at Massachusetts General Hospital, in Boston, MA. In 2006 he received the ESICM” Young investigator award”. In 2010 he acquired a PhD in Biomedical technology at UNIMIB. Research has always been complementary to his clinical activities. His research is largely focused on ARDS and mechanical ventilation monitoring. From October 2015 to October 2018 he was chairman of the Acute Respiratory Failure Section of ESICM. He is co-PI of the LUNG SAFE study (main manuscript published in 2016 on JAMA). He has participated to organization of several meetings and courses on mechanical ventilation. He authored about 170 peer-reviewed papers, mainly focused on invasive and non-invasive ventilation, 10 book chapters, two patents delivering about 120 invited talks. He is co-founder and president of Reviewer Credits, co-founder of DICO Technologies.