Microcirculation. From Bench to Bedside

I. Coronary microcirculation - Theoretical aspects
1.Basic concepts of microcirculation 2.Coronary microvascular dysfunction in cardiovascular disease: lessons from large animal models 3.Dynamic testing of microcirculation 4.Study of microcirculation through direct microscopic techniques 5.Platelet function and coronary microvascular dysfunction 6.Role of perivascular tissue in microvascular dysfunction 7.Myocardial infarction with non-obstructive coronary artery disease

II. Clinical cases
8.Role of coronary microcirculation in no-reflow phenomenon in myocardial infarction with ST segment elevation 9.Microcirculatory dysfunction in chronic angina 10.Vasospastic angina 11.Brain microcirculation and silent cerebral damage 12.Microcirculation and left ventricular hypertrophy 13.Microcirculatory dysfunction in acute heart failure 14.Relationship between coronary microcirculation and arrhythmias: a Janus with two faces

III. Therapeutical considerations
15.Treatment of no-reflow phenomenon 16.Lipid lowering treatment in microcirculation 17.Cell strategies to stimulate angiogenesis/vasculogenesis for improvement of microcirculation

This comprehensive reference book of coronary microcirculation broadly covers theoretical aspects, clinical cases and therapeutic considerations from an innovative perspective. Topics covered include: ischemic heart disease, silent cerebral damage, heart failure, left ventricular hypertrophy arrhythmias, and cerebral and renal microcirculation.

Microcirculation: From Bench to Bedside underlines the clinical importance of addressing coronary microcirculation with relevant clinical examples that are often encountered by practitioners. It therefore provides a critical resource on microcirculation for both specialist and non-specialist practitioners.

Maria Dorobantu is Professor of Cardiology at the University of Medicine and Pharmacy Carol Davila Bucharest, Romania, and head of the Cardiology Department of Clinical Emergency Hospital, Bucharest. She received a postdoctoral research grant from the French Government in 1991, conducting her research activity at University Paul Sabatier, Toulouse, France. She has a special interest in the assessment and treatment of heart failure and arterial hypertension. She is the President of the Romanian Society of Hypertension. Between 2008 and 2014 she was member of CPC of ESC, Group of Hypertension. Since 2016 she is the chairperson of the Coronary Pathophysiology and Microcirculation Working Group of European Society of Cardiology. Prof.Dorobantu is also a member of the Romanian Academy for Medical Sciences. She has published over 300 articles in highly qualified scientific journals with her work highly quoted in the scientific literature (Citations: over 2700; h-index 23). She is a corresponding member of the French Academy of Medical Sciences.

Lina Badimon is the Director of the Cardiovascular Research Center in Barcelona (CSIC-ICCC) in the Hospital Santa Creu and San Pau, Director of the Cardiovascular Research Chair of the Autonomous University of Barcelona and Director of the UNESCO Chair in Biomedical Sciences Training and Research. Her research activities focus on coronary artery disease, thrombosis and atherosclerosis and ischemic heart disease. She has published over 460 articles in highly qualified scientific journals with her work highly quoted in the scientific literature (Citations: over 21.504; h-index 64). She has written 230 reviews and book chapters. She is Member of Editorial Boards of various international scientific journals. Currently, Prof.Badimon is Vice-President of ESC in charge with Scientific Affairs (includes Working Groups, Councils and Women in Cardiology).