Clinical Neuroimmunology. Multiple Sclerosis and Related Disorders

Introduction to Neuroimmunology
Principles if Immunotherapy
The microbiome and the immune system
Multiple Sclerosis
Immunopathogenesis
Epidemiology and Genetics
Clinical features and diagnosis
Symptom Management
Disease modifying treatment
Multiple sclerosis in Children
Other Disorders
Acute Disseminated Encephalomyelitis (ADEM)
Neuromyelitis Optica
Neuroimmunology of Cancer
Autoimmune encephalitis
CNS Vasculitis
Neuroimmunology of CNS infections
Peripheral Nervous System Disorders
Immunologic disorders of Neuromuscular junction
Autoimmune Neuropathies
Systemic disorders
Systemic autoimmune diseases with neurologic manifestations

This comprehensive, up-to-date book is designed to make recent developments in neuroimmunology accessible to medical professionals in the field. The field of neuroimmunology is complex and rapidly evolving, especially with the current improvements in targeted biologic therapies. This resource concisely offers clear explanations of these scientific and clinical advancements.

Divided into five parts, the book begins with an in-depth introduction to neuroimmunology and the principles of immunotherapy. Section two consists of eight chapters devoted to multiple sclerosis, including discussions on the clinical features of the disease as well as symptom management and diagnosis. Subsequent chapters then dive into other central nervous system inflammatory disorders such as neuromyelitis optica, autoimmune encephalopathies, and immunological aspects of cancer. Following this are two chapters that examine distinct aspects of autoimmune disorders of the peripheral nervous system. Finally, the book closes with a review on the neurologic manifestations, diagnostic approaches and treatments of the various systemic rheumatic diseases.

Following its successful predecessor edition, Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders, Second Edition is positioned to be an invaluable asset to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.

Syed A. Rizvi, MD, EMHLAssociate ProfessorRhode Island HospitalDepartment of Clinical NeurosciencesProvidence, RI 02903

Jonathan F. Cahill, MDAssistant Professor of NeurologyRhode Island Hospital and Alpert Medical School of Brown UniversityDepartment of NeurologyProvidence, RI 02903

Patricia K. Coyle, MDProfessor and Vice Chair Director, MS Comprehensive Care Center Stony Brook University Medical Center Department of NeurologyStony Brook, NY 11794