Skin Decontamination. A Comprehensive Clinical Research Guide

Chapter 1. Isolated Human and Animal Stratum Corneum As a Partial Model for the 15 Steps of Percutaneous Absorption: Emphasizing Decontamination, Part I
Xiaoying Hui and Howard I. Maibach

Chapter 2. Isolated Human And Animal Stratum Corneum As A Partial Model For The 15 Steps Of Percutaneous Absorption: Emphasizing Decontamination Part II
Xiaoying Hui and Howard I. Maibach

Chapter 3. Recent Knowledge: Human/Animal Skin Decontamination
Christina Phuong and Howard I. Maibach

Chapter 4. The Decontamination of Chemically Contaminated Remains
Jill A. Harvilchuck, Dan Noort, Glenn Lawson, Kelly Kyburz, Miranda Verschraagen, and Alison Director-Myska

Chapter 5. Effectiveness of Chemical, Biological, Radiological, and Nuclear (CBRN) Skin Decontaminants: Towards Tests Standardization
Colonel Denis Josse

Chapter 6. Effects of Soap-Water Wash on Human Epidermal Penetration
Hanjiang Zhu1, Eui-Chang Jung, Christina Phuong, Xiaoying Hui, and Howard Maibach

Chapter 7. Fuller's Earth: Old and Faithful Skin Decontaminant Against Toxic Agents
Shlomit Dachir, Eliezer Fishbine, Yakov Meshulam, Hillel Buch, Nahum Allon, and Tamar Kadar

Chapter 8. Comparison of Four Different Fuller's Earth Formulations in Skin Decontamination
Annick Roul, Cong-Anh-Khanh Le, Marie-Paule Gustin, Emmanuel Clavaud, Bernard Verrier, Fabrice Pirot, and Francoise Falson

Chapter 9. The Mass Decontamination Paradigm: Response Relating to Gas Phase Exposures and Skin Decontamination
Christina Baxter, Sharyn Gaskin, Michael Logan, and Dino Pisaniello

Chapter 10. Binding Affinity and Decontamination of Dermal Decontamination Gel (DDGel) to Model Chemical Warfare Agent (CWA) Simulants
Yachao Cao, Akram Elmahdy, Hanjiang Zhu, Xiaoying Hui, and Howard Maibach

Chapter 11. Dermostyx (IB1): High-efficacy and Safe Topical Skin Protectant Against Percutaneous Toxic Agents
Shlomit Dachir, Izhak Barness, Eliezer Fishbine, Jacob Meshulam, Rita Sahar, Arik Eisenkraft, Adina Amir, and Tamar Kada

Chapter 12. Understanding the Impact of Responder Management Strategies on Public Experiences and Behaviour During Mass Decontamination
Holly Carter, John Drury, and Richard Amlot

The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to chemical warfare agents and toxic industrial chemicals because it decreases serious skin damage to the patient and, potentially, their doctor.

This multi-authored international text pulls together a century of decontamination research and helps the reader expedite solutions that will decrease morbidity and mortality. Complete with dozens of hiqh quality photographs and illustrations, Skin Decontamination aids industrial hygiene, dermatology, occupational physicians and those involved in the public health arena.

Hanjiang Zhu, PhD
University of California San Francisco, Dermatology
Department of Dermatology
2340 Sutter Street N461
San Francisco, CA 94143/0989
USA

Howard I. Maibach, MD
Professor, Dermatologist
University of California San Francisco
Department of Dermatology
2340 Sutter Street N461
San Francisco, CA 94143/0989
USA