Female Reproductive Dysfunction

Part I Hypothalamic-Pituitary-ovary axis disorders: The hypothalamus-pituitary-ovary axis.- The menstrual cycle and related disorders.- The Polycystic ovary syndrome.- The menstrual disorders related to endocrine diseases.- The menstrual disorders related to systemic diseases.- Hormones and sex behaviour.- Hormonal contraception.- Part II Uterine disorders: Endometriosis.- Uterine fibroids and adenomyosis.- Abnormal uterine bleeding.- Part III Infertility: Epidemiology and causes.- Diagnostic protocols.- Hormonal treatments.- Assisted reproductive technologies.- Part IV Menopause: Premature ovarian insufficiency.- The climacteric syndrome.- Long term effects.- HRT.- Menopause and bone metabolism.- Part V Pregnancy: Endocrinology of maternal-placental axis.- The "great obstetrical syndromes".- Part VI Breast: Hormones, breast disorders and lactation.

Written by leading international specialists, this book provides a comprehensive, state-of-the-art overview of endocrine-based female reproductive disorders. Particularly focusing on the Hypothalamus - Pituitary - Ovary (HPO) axis as the main driver of reproduction in women, it discusses amenorrhea; chronic anovulation and polycystic ovary syndrome as the most common dysfunctions of the HPO axis; endocrine diseases as possible impacts on the HPO axis; uterine disorders related to estrogen/progesterone; and the impact of endometriosis and uterine fibroids on reproduction. It also addresses infertility and menopause as hormone-related disorders in women and endocrine changes during pregnancy and lactation, and in breast disorders.

The book is intended as a major reference for endocrinologists, gynecologists, and obstetricians, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which provides access to live editions constantly updated through a dynamic peer-review publishing process.

Felice Petraglia is Professor and Chairman of Obstetrics and Gynecology and Director of the Residency Program in Obstetrics and Gynecology at the University of Florence (Florence, Italy).

Prof. Petraglia is President of the Society of Endometriosis and Uterine Disorders (SEUD) and fellow ad eundem of the Royal College of Obstetricians and Gynaecologists (RCOG). He was President of the Society for Gynecologic Investigation (SGI) (2008-2009), member of the Executive Board of the International Society of Gynecological Endocrinology (ISGE), and member of the International Federation of Gynecology and Obstetrics (FIGO) and of the European Board and College of Obstetrics and Gynecology (EBCOG).

Prof. Petraglia has received the award for the best publications of the Endocrine Society (2010) and the Award of the Society Reproductive Investigation (2014).

He is Editor of RBMO and is Associate Editor of Reproductive Science and Faculty 1000 Medicine (Section Head in Reproductive Endocrinology).

He was Editor-in-Chief of Journal of Human Reproduction Update (2013-2018) and of Journal of Endometriosis (2009-2012).

Prof. Petraglia is author or co-author of more than 920 peer-reviewed papers in Scientific International Journals (IF: 19886, HI:69) and co-editor of 27 scientific volume

Bart Fauser is a gynaecologist and Em. Professor of Reproductive Medicine, former Head of the Department for Reproductive Medicine and Gynaecology and Chair of the Division of Woman & Baby at the University of Utrecht and the University Medical Center Utrecht, The Netherlands.

He is a Fellow ad Eundum of the Royal College of Obstetrics and Gynaecology, Honorary member of ESHRE, Night in the order of the Netherlands Lion, member of the (US) National Academy of Medicine, member of the board of the Dutch Medical Research Counsel (ZonMW), Editor in Chief of Reproductive Biomedicine Online (RBMO), and executive Board member of International Federation of Fertility Societies (IFFS).

He previously held posts as a Fulbright scholar at the University of California, San Diego; visiting professorships at Stanford University School of Medicine, California, USA; Free University, Brussels, Belgium; University of Siena, Italy; University of Southampton, United Kingdom; and the University of Adelaide, Australia. He was a past chair of the World Health Organization (WHO) steering committee for infertility guidelines and past Editor-in-Chief of Human Reproduction Update.

His major research interests include the pathophysiology of human ovarian function, PCOS, POI, IVF and women's health. He has published over 450 peer-reviewed articles (Hirsch factor > 100), and his work has been widely covered in the national and international lay press.