PART 1: BIOFILMBIOFILM: HISTORY, CAUSE AND TREATMENT.- HOST ENVIRONMENTAL SIGNALS AND EFFECTS ON BIOFILM FORMATION.- CHRONIC WOUND BIOFILM MODEL.- COMBATING BIOFILMS IN THE CHRONIC WOUND.- BIOFILM: CLINICAL EXPERIENCE.- MIXED-SPECIES BIOFILM COMPROMISES WOUND HEALING BY DISRUPTING EPIDERMAL BARRIER FUNCTION.- ANTI-BIOFILM AGENTS.- ANTI-BIOFILM PROPERTIES OF WOUND DRESSING INCORPORATING NONRELEASE POLYCATIONIC ANTIMICROBIALS.- ANTI-BIOFILM PEPTIDES AS A NEW WEAPON IN ANTIMICROBIAL WARFARE.- DILUTED HONEY INHIBITS BIOFILM FORMATION: POTENTIAL APPLICATION IN URINARY CATHETER MANAGEMENT?.- ANTIBIOFILM EFFICACY OF HONEY AND BEE-DERIVED DEFENSIN-1 ON MULTI-SPECIES WOUND BIOFILM.- GENES ENCODING ADHESION FACTORS AND BIOFILM FORMATION IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS IN MOROCCO.- ANTI-BIOFILM ACTIVITY OF BACTERIOPHAGES - MECHANISMS AND IMPACT ON CLINICAL PRACTICE.- SERRATIA SECONDARY METABOLITE PRODIGIOSIN INHIBITS PSEUDOMONAS AERUGINOSA BIOFILM DEVELOPMENT BY PRODUCING REACTIVE OXYGEN SPECIES THAT DAMAGE BIOLOGICAL MOLECULES.- ENHANCED INHIBITION OF BACTERIAL BIOFILM FORMATION AND REDUCED LEUKOCYTE TOXICITY BY CHLORAMPHENICOL: -CYCLODEXTRIN:N-ACETYLCYSTEINE COMPLEX.- LIPOPEPTIDES FROM BACILLUS SUBTILIS AC7 INHIBIT ADHESION AND BIOFILM FORMATION OF CANDIDA ALBICANS ON SILICONE.- NEW BISPHOSPHONATE MONOMERS AND POLYMERIC NANOPARTICLES FOR BIOMEDICAL APPLICATIONS: ANTIBACTERIALS AND INHIBITION OF BIOFILM FORMATION.- SIMPLE AND RAPID METHOD FOR DETECTING BIOFILM FORMING BACTERIA.- AN EFFICIENT ONE-POT SYNTHESIS OF THIOCHROMENO[3,4-D]PYRIMIDINES DERIVATIVES: INDUCING ROS DEPENDENT ANTIBACTERIAL AND ANTI-BIOFILM ACTIVITIES.
PART 2: PILONIDAL CYSTS AND SINUSES: HISTORY AND GENERAL INFORMATION ON PILONIDAL CYSTS AND SINUSES.- PILONIDAL DISEASE.- PILONIDAL SINUS DISEASE.- THERAPY OF PILONIDAL SINUS--IS MORE ALWAYS BETTER.- PILONIDAL SINUS: INCLUDING UMBILICAL PILONIDAL SINUS.- OPEN PILONIDAL WOUND TREATMENT.- THE EFFECT OF PHENOL CONCENTRATION ON THE TREATMENT OF PILONIDAL SINUS DISEASE.- CRYSTALLIZED OR LIQUID PHENOL APPLICATION IN PILONIDAL SINUS TREATMENT.- TOPICAL AGENTS AND DRESSINGS FOR PILONIDAL SINUS WOUND HEALING BY SECONDARY INTENTION.- MODIFIED OFF-MIDLINE CLOSURE OF PILONIDAL SINUS DISEASE.- CLEFT LIFT PROCEDURE FOR PILONIDAL DISEASE.- COMPARISON OF CONVENTIONAL INCISION AND DRAINAGE FOR PILONIDAL ABSCESS VERSUS NOVEL ENDOSCOPIC PILONIDAL ABSCESS TREATMENT.- LEARNING CURVE FOR PILONIDAL SINUS SURGERY.- RISK FACTORS FOR PILONIDAL SINUS DISEASE IN TEENAGERS.- COMPARISON OF TREATMENTS FOR AN INFECTED PILONIDAL SINUS: DIFFERENCES IN SCAR QUALITY AND OUTCOME BETWEEN SECONDARY WOUND HEALING AND LIMBERG FLAP.- MINIMAL EXCISION AND PRIMARY SUTURE IS A COST-EFFICIENT DEFINITIVE TREATMENT FOR PILONIDAL DISEASE WITH LOW MORBIDITY.- MINIMALLY INVASIVE SURGICAL APPROACH TO COMPLICATED RECURRENT PILONIDAL SINUS.- COMPARISON OF MIDLINE AND OFF-MIDLINE CLOSURE TECHNIQUES IN PILONIDAL SINUS SURGERY.- APPLICATION OF FASCIOCUTANEOUS V-Y ADVANCEMENT FLAP IN PRIMARY AND RECURRENT SACROCOCCYGEAL PILONIDAL SINUS DISEASE.- TANDEM RHOMBOID FLAP REPAIR: A NEW TECHNIQUE IN TREATMENT OF EXTENSIVE PILONIDAL DISEASE OF THE NATAL CLEFT.- CONSERVATIVE VS SURGICAL INTERVENTIONS FOR UMBILICAL PILONIDAL SINUS.
This book discusses the latest findings in the fields of biofilm, pilonidal cysts and sinuses. The first part provides detailed information on biofilm formation, antibiofilm properties and activity as well as their potential clinical application in wound management. The second part then examines pilonidal sinus disease and the surgical treatment options. Written by leading experts in the field, the book is a valuable resource for beginners and experienced surgeons alike.
Dr. Melvin A. Shiffman, MD, JD, FCLM, received his MD from Northwestern University School of Medicine in 1957 and completed his residency in general surgery in 1964 at the Veterans Administration Hospital, Long Beach, California. Since then he has been continuously involved in oncologic surgery, reconstruction, and cosmetic surgery. In 2002, Dr. Shiffman became Chair of the Section of Surgery at Tustin Hospital and Medical Center and in 2009-10 he served as President of the American College of Legal Medicine. He is Editor Emeritus of the American Journal of Cosmetic Surgery, a member of the Scientific Committee of the American Journal of Aesthetic Medicine, and an examiner for the International Board of Cosmetic Surgery. He is also a former Editor-in-Chief of both the American Journal of Cosmetic Surgery and the International Journal of Cosmetic Surgery. Dr. Shiffman is the recipient of many honors and is a fellow of various colleges and societies. He has published 300 articles, authored or edited 34 books, and written more than 140 book chapters.
Dr. Mervin Low, MD received his MD from the University of British Columbia, Vancouver, BC, Canada. He completed his Plastic Surgery Residency at the University of Manitoba, Winnipeg, MB, Canada, and a Breast and Aesthetic Surgery fellowship at Georgetown University in Washington, DC, USA, and at the Plastic Surgery Center of the Pacific, Honolulu, HI, USA. Dr. Low has a busy practice devoted entirely to Aesthetic and Reconstructive Plastic Surgery. He is a prolific author, educator and innovator. He has been recognized locally as one of the Best Doctors in California and nationally as one of the Top Plastic Surgeons in America.