1- General considerations.
2- Respiratory Manifestations of Combined T- and B-Cell Immunodeficiencies.
3- Respiratory Manifestations of Predominantly Antibody Deficiencies.
4- Respiratory Manifestations of Congenital Defects of Phagocytes.
5- Respiratory Manifestations of Genetic Disorders of Immune Regulation.
6- Respiratory Manifestations of Defects in Innate Immunity.
7- Respiratory manifestations of Autoinflammatory Disorders.
8- Respiratory manifestations of Complement Deficiencies.
9- Respiratory manifestations of Other Well-Defined Immunodeficiencies.
10- Treatment of Respiratory Manifestations in PIDs.
This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice.
Nima Rezaei, MD, PhD is the Professor of Clinical Immunology and Deputy President of Research Center for Immunodeficiencies. He gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained a MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Since 2010, Dr. Rezaei has worked at the Department of Immunology and Biology, School of Medicine, Tehran University of Medical Sciences; he is now the Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences. In addition, he is also the founding president of Universal Scientific Education and Research Network (USERN). Dr. Rezaei has already been the Director of more than 50 research projects and has designed and participated in several international collaborative projects. Dr. Rezaei is an editorial assistant or board member for more than 20 international journals. He has edited more than 10 books, has presented more than 400 lectures/posters in congresses/meetings, and has published more than 650 articles in the international scientific journals during the last decade.
Seyed Alireza Mahdaviani, MD is head allergist and clinical immunologist at the National Research Institute of Tuberculosis and Lung Diseases (NRITLD), the largest referral center for pulmonary diseases in Iran. He is specialized in the diagnosis and management of patients suffering from immunodeficiency. As an Associate Professor of Allergy and Clinical Immunology with experiences and interest in immunology and pulmonary research, Dr. Mahdaviani teaches and trains fellows, residents, and medical students the clinical knowledge and research skills in allergy, immunology, and pulmonary medicine. He is an Editorial board member of the Iranian Journal of Allergy, Asthma and Immunology and a member of the managerial board of Iranian Society of Asthma and Allergy.