The 25th edition of our Guide to HIV/AIDS Therapy provides practical clinical guidance for the treatment of HIV and AIDS, based on the latest available evidence. Popular with physicians, pharmacists, physician assistants, nurse practitioners, and other clinicians, the Sanford Guide to HIV/AIDS Therapy provides information that is convenient, concise, and reliable. This latest edition includes numerous updates, including the latest fixed dose combination and more convenient once-daily formulations of ARV drugs. The Pediatric section (Table 8) has been updated extensively and includes an updated listing of liquid formulations of ARV drugs. The sections on HIV diagnostics (Table 3), differential diagnosis of HIV/AIDS-related clinical syndromes and opportunistic infections (OIs), immune reconstitution and treatment of specific OIs (Tables 11 and 12) continue to be refined and updated to better reflect what is encountered in persons with HIV and AIDS today.