This book documents the consequences of the exposure of infants to the influence
of intrauterine chemicals. In setting out the evidence for these outcomes, the
authors demonstrate that decisions about care and management can and should
be made as early as possible. This should allow professionals to provide protective
management and prevent the delays that are so often seen in this area of medical
and social care.
The international team of contributors sets out to inform the reader of the potential risks to infants exposed to a range of intrauterine chemicals that are potentially neuroactive, including medicinal drugs such as antiepileptics, antidepressants and antipsychotics, as well as drugs of abuse, including alcohol, opiates, and recreational drugs such as cannabis and tobacco. They review the teratogenic action of some of the chemical processes and the relationship of exposure to the stage of pregnancy. Some agents alter anatomic structure; others alter the chemical balance of neurotransmitters and may thus alter the regulation of brain function, with profound effects on the child's behaviour and propensity to behavioural disturbances. The book explores strategies to support these children and those who care for them, including statutory agencies.
Table of Contents
Contents 1. INTRODUCTION Philip Preece (Chesterfield, UK)2. EPIDEMIOLOGY OF DRUG AND ALCOHOL USE DURING PREGNANCY Ron Gray (Oxford, UK)3. NORMAL AND ABNORMAL EMBRYOGENESIS OF THE MAMMALIAN BRAIN Kathy Sulik, Shonagh O'Leary-Moore, Elizabeth Godin, and Scott Parnel (Chapel Hill, NC, USA)4. EPILEPSY IN PREGNANCY AND THE EFFECT OF PRENATAL ANTIEPILEPTIC MEDICATION Jill Clayton Smith (Manchester, UK) and Gus Baker (Liverpool, UK)5. NEURODEVELOPMENT OF CHILDREN EXPOSED TO ANTIDEPRESSANT AND ANTIPSYCHOTIC MEDICATIONS DURING PREGNANCY Irena Nulman, Sara Citron, Michelle Todorow, and Elizabeth Uleryk (Toronto, Canada)6. DIAGNOSIS OF THE FETAL ALCOHOL SYNDROME: EMPHASIS ON EARLY DETECTION Margaret Barrow (Leicester, UK) and Edward P. Riley (San Diego, CA, USA)7. THE EFFECTS OF PRENATAL ALCOHOL EXPOSURE ON BRAIN AND BEHAVIOR Christie L. McGee and Edward P. Riley (San Diego, CA, USA)8. EFFECT OF DRUGS ON THE FETUS: OPIATES INCLUDING HEROIN AND COCAINE Lynn T Singer and Sonia Minnes (Cleveland, OH, USA)9. MARIJUANA USE DURING PREGNANCY: ITS EFFECTS ON OFFSPRING FROM BIRTH TO YOUNG ADULTHOOD Peter A. Fried (Ottawa, Canada)10. IN-UTERO EXPOSURE TO THE POPULAR RECREATIONAL' DRUGS MDMA (ECSTACY) AND METHAMPHETAMINE (ICE, CRYSTAL): PRELIMINARY FINDINGS Derek Moore (London, UK), John. J.D. Turner (London, UK), Julia E. Goodwin (London, UK), Sarah E. Fulton (Cleveland, OH, USA), Lynn T. Singer (Cleveland, OH, USA) and Andrew C. Parrott (Swansea, UK)11. THE SHORT-TERM AND LONG-TERM DEVELOPMENTAL CONSEQUENCES OF MATERNAL SMOKING DURING PREGNANCY Kate E. Pickett (York, UK) and Lauren S. Wakschlag (Chicago, IL, USA)12. MANAGEMENT OF THE EFFECTS OF PRENATAL DRUGS IN CHILDREN OF DRUG ABUSING PARENTS Faye Macrory and Michael Murphy (Manchester, UK)13. PRENATAL AND POSTNATAL INTERVENTION STRATEGIES FOR ALCOHOL-ABUSING MOTHERS IN PREGNANCY Ann P. Streissguth and Therese M. Grant (Seattle, WA, USA)14. COGNITIVE AND BEHAVIORAL INTERVENTIONS TO AMELIORATE THE EFFECTS OF FASD IN CHILDREN AND ADOLESCENTS Wendy O. Kalberg (Albuquerque, NM, USA) and Julie Gelo (Bothell, WA, USA)15. FETAL TERATOGEN SYNDROMES: PSYCHIATRIC ASPECTS AND MANAGEMENT David J. Bramble (Telford, UK)