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Brain Protection in Cardiac Surgery
Bonser, R. — Pagano, D. — Haverich, A.
1ª Edición Enero 2011
Inglés
Tapa dura
248 pags
771 gr
20 x 27 x 2 cm
ISBN 9781849962926
Editorial SPRINGER
LIBRO IMPRESO
-75%
155,99 €39,00 €IVA incluido
149,99 €37,50 €IVA no incluido
Producto en Liquidación
About this book.
Brain injury remains one of the most dreaded complications of cardiac surgery.
The range of injury is broad; while a stroke may be easily defined and diagnosed,
more subtle injuries most definitely occur. There remains debate as to how these
are diagnosed and there is a lack of standard definitions allowing inter-study
comparison. If we are to have confidence in strategies that may reduce brain
injury, we need to have confidence in the end-points used to define that injury.
We need to better understand the phenomena associated with neuropsychometric
testing; we need to fully elucidate the relationship between structural brain
injury, embolism counting, and surrogate biomarkers; and we need an improved
understanding of the clinical significance of abnormalities detected on postoperative
magnetic resonance imaging. Brain Protection in Cardiac Surgery presents a detailed
background of studies of neurological morbidity and neuroprotection from a range
of experts in the field of neuroprotection, providing a detailed reference for
clinicians in the field. The Editors have detailed connections between the different
strands of injury — be it the pathology, the imaging, the clinical and
cognitive examination, potential biomarkers — and have then provided summary
reports of treatment strategies that may reduce such injury. As we look to the
future, the design of studies attempting to reduce such injury becomes increasingly
important and this book provides the fundamental background information to fuel
interest, initiate novel prevention and therapeutic strategies, and inform the
investigator how to develop and design their research study.
Content Level » Professional/practitioner
Related subjects » Cardiology & Angiology - Internal Medicine - Neurology - Radiology - Surgery
Table of contents
Section 1: The brain injury of cardiac surgery
1.1 Cerebral physiology and metabolism
1.2 The molecular and biochemical basis of brain injury and heart surgery –
Interventions for the future
1.3 The cardiopulmonary bypass circuit and the brain
1.4 The neurological sequelae of cardiac surgery
1.5 The incidence, pre-operative risk factors and long-term outcome of subtle
brain injury and cardiac surgery
1.6 The neuropathology of brain injury in cardiac surgery
1.7 Inflammatory response and the brain
1.8 The impact of brain injury on post-surgical quality of life
Section 2: The assessment of brain injury
2.1 The utility of neuropsychometric analysis following cardiac surgery
2.2 Pitfalls of neuropsychometric assessment and alternative investigative approaches
2.3 Imaging of the brain in cardiac surgery as a tool in brain protection studies
2.4 Current techniques of emboli detection and their utility in brain protection
studies
2.5 Intra-operative brain monitoring in cardiac surgery
2.6 The design of brain protection studies in the 21st century
Section 3: Reducing brain injury in cardiac surgery
3.1 Temperature and brain protection in cardiac surgery
3.2 Studies of non-pharmacological interventions to reduce brain injury
3.3 Pharmacological studies to reduce brain injury following cardiac surgery
3.4 Off-pump and on-pump coronary artery surgery and the brain
3.5 Experimental basis and clinical studies of brain protection in paediatric
heart surgery
3.6 Experimental basis and clinical studies of brain protection in aortic arch
surgery
Section 4: The future
4.1 The future of brain protection in cardiac surgery
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