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Molecular Exploitation of Apoptosis Pathways in Prostate Cancer (Molecular Medicine and Medicinal Chemistry, Vol. 5)
Kyprianou, N.
1ª Edición Marzo 2012
Inglés
Tapa dura
232 pags
1500 gr
null x null x null cm
ISBN 9781848164499
Editorial Imperial College Press
LIBRO IMPRESO
-5%
82,45 €78,33 €IVA incluido
79,28 €75,32 €IVA no incluido
Recíbelo en un plazo de
2 - 3 semanas
Description
This book focuses on the functional significance of targeting apoptosis for
the treatment of prostate cancer. New concepts on the challenges relating to
the development of resistance by androgen-independent tumors are introduced,
in terms of the contribution of anoikis and cross-talk of androgens with key
growth factor signaling pathways. This volume also provides insightful discussion
on the exploitation of the apoptotic and angiogenic synergism towards complete
eradication of prostate tumors. Last but not least, it includes reflections
on the drug development challenge based on analysis of data from existing clinical
trials.
By Natasha Kyprianou (University of Kentucky, USA)
Contents:
The Prostate Gland Dynamics
Apoptosis Signaling Pathways: Defined Routes to Eliminate Cancer Cells
Androgen Receptor-Mediated Apoptosis: Significance in Development of Hormone
Refractory Prostate Cancer
Anoikis in Prostate Cancer Metastasis
Novel Molecular Therapeutics for Targeting of Androgen-Independent Prostate
Cancer
Summary and Future Directions
Readership: Practising clinicians including urologists, pathologists,
medical oncologists and scientists with an interest in cancer, especially prostate
cancer.
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