Merkel Cell Carcinoma. a Multidisciplinary Approach (Molecular Medicine and Medicinal Chemistry, Vol. 2)

Description

Merkel cell carcinoma is an uncommon but not rare aggressive cutaneous malignancy. It has many similarities to melanoma, particularly in the need for aggressive multidisciplinary treatment, but far less is known about this disease by most practicing physicians. This book summarizes all of the existing knowledge about Merkel cell carcinoma and provides a much-needed perspective on future opportunities for diagnostic and therapeutic advances. It offers practical “how to” advice on diagnosis, treatment and follow-up, and also insight into how to establish a multidisciplinary Merkel cell carcinoma clinic. In addition, it will serve as a unique resource for trainees (medical students, residents and fellows) as well as for Merkel cell carcinoma patients and their advocates and caregivers. There is currently no such textbook, even an outdated one, covering this topic.

Edited by Vernon K Sondak (H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA), Jane L Messina (H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA), Jonathan S Zager (H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA), & Ronald C DeConti (H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA)

Contents:

• Epidemiology and Etiology of Merkel Cell Carcinoma (M Agelli & L X Clegg)
• Basic Pathobiology of Merkel Cell Carcinoma (J C Becker et al.)
• Association Between Merkel Cell Polyomavirus and Merkel Cell Carcinoma (D E Rollison & J C Becker)
• Discovering Merkel Cell Carcinoma Through Gene Expression Profiling (A T Weeraratna)
• Pathology of Merkel Cell Carcinoma (J L Messina)
• Clinical Recognition and Diagnosis of Merkel Cell Carcinoma (M H Lien et al.)
• Current Staging Systems for Merkel Cell Carcinoma (B D Lemos & P Ngheim)
• New Prognostic Factors in Merkel Cell Carcinoma (C Knapp et al.)
• Imaging of Merkel Cell Carcinoma (S Brodsky et al.)
• Surgical Management of Merkel Cell Carcinoma (M D Prince et al.)
• Special Considerations in the Surgical Management of Merkel Cell Carcinoma in the Head and Neck (M L Aya-Ay et al.)
• The Role of Mohs Micrographic Surgery in Merkel Cell Carcinoma (B S Cherpelis)
• Radiation in the Management of Primary and Regional Merkel Cell Carcinoma (G Hruby & J F Thompson)
• Management of Recurrent and Metastatic Merkel Cell Carcinoma (R C DeConti)
• Adjuvant Chemotherapy of Merkel Cell Carcinoma (R C DeConti)
• The Potential for Targeted Therapy of Merkel Cell Carcinoma (W A Samlowski & J C Becker).)
• Potential for Immunotherapy in Merkel Cell Carcinoma (K M McLean et al.).)
• Establishing a Multidisciplinary Merkel Cell Carcinoma Clinic (E C Bailey et al.)

Readership: Academics (cancer researchers); professionals (medical oncologists, surgical oncologists, radiation oncologists, pathologists, radiologists, family practice/internal medicine practitioners, dermatologists, head & neck surgeons, plastic surgeons, general surgeons); medical students; residents in radiation oncology, pathology, radiology, family practice/internal medicine, head & neck surgery, dermatology, general surgery, plastic surgery; fellows in medical oncology, surgical oncology, dermatopathology, dermatologic surgery; general public (Merkel cell carcinoma patients, their relatives, caregivers and advocates).