Therapeutic Strategies in Rheumatology

Description

Therapeutic Strategies in Rheumatology offers a global perspective on current approaches to diagnosis and therapy for musculoskeletal and joint disease, reporting on the latest clinical trials and 'breaking news' that will have an impact on future treatment strategies. In this book, experts in each of these fields guide the reader through the many options now available to clinicians combating these diseases, providing a clear account of current best practice and possible future developments. It has been well reported in recent trials that early inflammatory arthritis responds well to prompt, aggressive treatment with biologics and combination therapy. In addition to anti-TNF, newer biological agents are now emerging that block other mediators of inflammation and damage, and continuing advances in pharmacogenetics permit individually tailored therapeutic regimes that balance efficacy and toxicity. Additionally, in osteoporosis, a bewildering array of therapeutic options is available – the challenge for the clinician is deciding on which is appropriate for each patient. Progress is also being made in understanding and treating the numerous complications concomitant with rheumatic disease, particularly pulmonary hypertension. This publication addresses these issues in-depth, and presents a valuable resource for clinicians to stay abreast of latest developments.

Contents

1. Early inflammatory arthritis, JL Nam, E Villeneuve, P Emery
2. Established rheumatoid arthritis, PJ Barendregt, JMW Hazes
3. Beyond anti-TNF: other biological drugs in inflammatory arthritis, PC Taylor
4. Pharmacogenetics of inflammatory arthritis, J Wessels, T Huizinga, H-J Guchelaar
5. Psoriatic arthritis, E Pontifex, O Fitzgerald
6. Ankylosing spondylitis, J Braun
7. Systemic lupus, T Y-T Lu, JM Pego-Reigosa, D Isenberg
8. Antiphospholipid syndrome, C Edwards, G Hughes
9. Systemic sclerosis, EC Derrett-Smith, C Denton
10. Inflammatory myositis, D Scott
11. Disease modifying drugs in osteoarthritis, A Colebatch, N Arden
12. Gout, M Doherty, E Roddy
13. Osteoporosis, I Pande

Abbreviations
Index

Benefits
- Translates scientific evidence into improved clinical outcomes - Provides doctors with comprehensive overview of new developments from bench to bedside - Significant focus on disease mechanisms and emerging therapies in inflammatory arthritis

Readership
Specialists in rheumatology and internal medicine ? Hospital pharmacists ? Doctors in training

Edited by
Michael Doherty, Professor of Rheumatology, Academic Rheumatology, Nottingham City Hospital, Nottingham, UK