Intra-Uterine Insemination. Evidence Based Guidelines for Daily Practice

Description

Intra-uterine insemination (IUI) is a widely used fertility treatment for couples with unexplained and male subfertility. Although it is less invasive and less expensive than l other treatment options such as in vitro fertilization, several factors affect its outcome. In addition, IUI remains controversial due to concerns about some of the possible aspects of treatment, including side-effects such multiple pregnancies. This comprehensive evidence-based book from an international IUI expert team explores all of these topics and provides clear guidelines for daily practice.

Contents

General Introduction to Intra-Uterine Insemination (IUI) as a Treatment for Subfertility: The Impressions of an Old-Timer
Egbert te Velde

Diagnostic Work-Up before IUI
Janne-Meije van Weert, Harold Verhoeve, and Ben Willem Mol

When to Start IUI?
Pieternel Steures and Jan Willem van der Steeg

Indications for IUI
Ben Cohlen and Hasan N. Sallam

Immunologic Male Infertility
Benny Verheyden

Factors Influencing IUI Outcome: Female Age
Felicia Yarde and Frank J.M. Broekmans

Factors Influencing IUI Outcome: Male Age
Michael de Brucker and Herman Tournaye

Factors Influencing IUI Outcome: Weight Influences
John C. Petrozza, Irene Dimitriadis, and Pratap Kumar

Factors Influencing IUI Outcome: Semen Quality
Willem Ombelet, Nathalie Dhont, and Thinus Kruger

Factors Influencing IUI Outcome: Semen Preparation Techniques
Martine Nijs and Carolien M. Boomsma

Factors Influencing IUI Outcome: Time Interval as a Prognostic Factor
Roberto Matorras, Olga Ramón, Beatriz Corcostegui, Lorena Crisol, and Antonia Exposito

Factors Influencing IUI Outcome: Number of Cycles to Perform
Inge M. Custers

Factors Influencing IUI Outcome: Perifollicular Flow and Endometrial Thickness
Geeta Nargund, Vasileios Sarafis, and Stuart Campbell

Factors Influencing IUI Outcome: Timing and Number of Inseminations per Cycle
Astrid E.P. Cantineau and Ben Cohlen

Factors Influencing IUI Outcome: Site of Insemination in Therapeutic Donor Insemination
Femke P.A.L. Kop

Factors Influencing IUI Outcome: Immobilization after IUI
Inge M. Custers

Factors Influencing IUI Outcome: Ovarian Hyperstimulation
Ben Cohlen, Rosa Tur, and Rosario Buxaderas

Factors Influencing IUI Outcome: Luteal Phase Support
Ahmet Erdem

Fallopian Sperm Perfusion: Evidence on IUI versus Fallopian Sperm Perfusion
Willem Ombelet, Arne Sunde, and Jarl A. Kahn

Media Supplements: Platelet Activating Factor Improves Sperm Motility and IUI Outcomes
Linda M. Street, Bonnie Patel, and William E. Roudebush

Oxidative Stress and IUI Outcomes
Alaa Hamada, Ashok Agarwal, and Sergio Oehninger

Cost-Effectiveness of IUI
Lobke M. Moolenaar, Ben Willem Mol, and Bradley J. Van Voorhis

Minimal Standards and Organization for Donor Sperm Banking
Nicolás Garrido and Antonio Pellicer

Indications for Donor Sperm Including Lesbian Couples and Single Women
Anne Brewaeys

IUI and Psychological Aspects
Chris Verhaak and Jacky Boivin

Risk Factors for Higher-Order Multiple Pregnancies Following Stimulated IUI
Alexandra J. Bensdorp, Ben Willem Mol, and Fulco van der Veen

Prevention of Multiple Pregnancies after IUI
Diane de Neubourg, Jan Bosteels, and Thomas D’Hooghe

Perinatal Outcome after IUI
Willem Ombelet and Petra de Sutter

IUI-Associated Infection Risks and Preventative Measures
Carin Huyser

Cancer and Semen Preservation
Roelof Menkveld

Preconception Gender Selection: Laboratory Aspects
Lars Björndahl

Preconception Sex Selection: Ethical Evaluation
Guido Pennings

Factors Affecting the Success of IUI: Implications for Developing Countries
Hasan N. Sallam

SWOT Analysis of Accessible IUI in Developing Countries, Resource-Poor Settings, and Primary Care Centers
Willem Ombelet and Sheryl Vanderpoel

Summary: Levels of Evidence of All Statements
Summary: Grade of Strength of All Recommendations