Pharmacotherapies for the Treatment of Opioid Dependence. Efficacy, Cost-Effectiveness and Implementation Guidelines

The most comprehensive text of its kind, this book addresses the management of opioid withdrawal and opioid maintenance therapy, combining up-to-date reviews of scientific literature with evidence-based clinical guidelines for relevant pharmacotherapies.

It presents:

• information on the cost-effectiveness of the various types of opioid treatment
• pharmacotherapies used for the management of opioid dependence
• knowledge from international research literature on the value and relative efficacy of the various pharmacological approaches

This guide includes pharmacotherapies used in the management of withdrawal from opioids such as clonidine, lofexidine, methadone, buprenorphine and naltrexone and also symptomatic medications. It also includes different forms of maintenance therapy using opioid agonists such as methadone, LAAM, buprenorphine, slow-release oral morphine and diamorphine, and opioid antagonists such as naltrexone.