• Builds on the successful formula of 22 previous volumes
• Presents cutting-edge articles on hot topics by experts of international renown
• All articles aim to be of interest to both practising and trainee anaesthetists
Preface; 1. Pharmacogenomics: the genetic basis for variability in drug response B. P. Sweeney; 2. The opioid receptor and opioid peptides C. Zöller and C. Stein; 3. Coagulation M. Laffan; 4. Anaesthetic agents and myocardial protection W. Schlack and D. Ebel; 5. The treatment of heart failure due to left ventricular systolic dysfunction R. S. Gardner and T. A. McDonagh; 6. Blunt chest trauma A. R. Edouard, V. Minville and L. Martin; 7. Function haemodynamic monitoring R. Chavko and M. R. Pinsky; 8. Sepsis and the use of Xigris® J.-L. Vincent; 9. Selective decontamination of the digestive tract - why don't we apply evidence to practice? H. K. F. van Saene, N. Taylor, S. P. Barrett, K. Lowry and R. E. Sarginson; 10. Glycaemic control and outcome in intensive care D. Mesotten, I. Vanhorebeek and G. Van den Berghe; 11. Substance use disorders and anaesthesia J. Jage.