Toxicology. the Past, Present, and Future of Basic, Clinical and Forensic Medicine, Vol. 1

Description

This book offers readers an overview of the field of toxicology while incorporating historical context with present day advances. The chapters, written in a style that facilitates the reader's connection of past developments with the present state-of-the-art practices in specific fields of toxicology, provide a detailed coverage of diverse areas in toxicology. The areas of chapters chosen for detailed discussion are characteristic of the overall field and helps to reinforce the basic principles of toxicology. As such, this book will be a valuable resource not only for those scientists in the field of toxicology, but also for those in related fields (e.g., pharmacology, physiology, microbiology, biochemistry, immunology and others). Additionally, this book will be a valuable resource for teaching graduate students in not only toxicology, but also in the related fields above. While this book is not primarily intended as an introductory text for undergraduate students' first exposure to the field of toxicology, it would serve very useful as a text for an advanced undergraduate level biology or chemistry course. The chapters are filled with appropriate tables and figures which help illustrate and reinforce the information in each chapter. The referencing of material cited is carefully prepared and provides links to additional information that will aid the reader in understanding and appreciating the information within the text. The reader will find this book to be of significant depth and breadth so as to meet the needs of many groups of students and established scientists. 

Table of contents

Foreword
Preface

Chapter 1
Environmental Toxicology: Significance of TNF-α Signaling in Environmental Cardio-Toxicity
(Rajat Sethi, Mina Al-Shahed, California Health Sciences University, Clovis, California, USA)
pp. 1-24

Chapter 2
Dermatotoxicology
(Chandra Sekhar Kolli, Parveen Sultana Janampet, Mamatha Tirunagari and Kc Taylor, California Health Sciences University, California, USA)
pp. 25-44

Chapter 3
Safety and Toxicity of Nanoparticles in Medicine
(Muhammad Delwar Hussain and Matthew Ogbuehi, College of Pharmacy, California Health Sciences University, Clovis, CA, USA)
pp. 45-68

Chapter 4
Structure and Functional Relationships in Clostridium Perfringens Toxins
(Ajit K Basak, Claire E Naylor, Christos G Savva, Jessica Huyet and Richard W Titball, School of Biological Sciences, Birkbeck College, London, UK, and others)
pp. 69-100

Chapter 5
Computational Toxicology: Predicting Toxicity of Chemicals Using Mathematical Chemodescriptors and Biodescriptors
(Subhash C. Basak, International Society of Mathematical Chemistry, Duluth, MN, USA, and others)
pp. 101-114

Chapter 6
Modelling and Simulations of Pharmacokinetics and Pharmacodynamics in Virtual Populations to Enhance Understanding of Toxicology in Humans
(Manoranjenni Chetty, Barbara Wisniowska, Sebastian Polak, Simcyp Ltd, UK, and others)
pp. 115-134

Chapter 7
Air Pollution Toxicity and its Impact on Public Health
(Robert Clegg, California Health Sciences University, College of Pharmacy, Clovis, CA, USA)
pp. 135-170

Chapter 8
Forensic Toxicology
(Gamal Hussein, Professor of Pharmacy, South College School of Pharmacy, Knoxville, TN, USA and others)
pp. 171-184

Chapter 9
LC-MS-based Metabolomics in Drug-induced Liver Injury
(Feng Li, Ming Q. Weib, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA, and others)
pp. 185-212

Chapter 10
Current Reproductive and Developmental Toxicology: Focus on Experimental Studies
(Juliana E Perobelli, Departamento de Ciências do Mar, Universidade Federal de São Paulo, UNIFESP, Baixada Santista, Santos/SP, Brasil)
pp. 213-234

Chapter 11
Toxicity Predicted through Multimodal Sensing Systems and Algorithms -Neuropsychological Toxicity in Stress Predicted through a Primate Model, Common Marmoset (Callithrix Jacchus) of Dietary Therapy with Novel Multimodal Sensing Systems and Algorithms
(Mamiko Koshiba, Saitama Medical University, Japan)
pp. 235-264

Index