Dexamethasone. Therapeutic Uses, Mechanism of Action and Potential Side Effects (Pharmacology - Research, Safety Testing and Regulation Series)

Description

Dexamethasone is a potent, long-term acting synthetic glucocorticoid class of steroid drugs that have anti-inflammatory and immunosuppressant properties. The authors in this book discuss the therapeutic uses, mechanisms of action and potential side effects of dexamethasone. Topics include dexamethasone for the treatment of meconium aspiration syndrome (MAS); dexamethasone effects in hyperinfection syndrome due to strongyloidiasis; dexamethasone use in retinal disease and anti-tumour activities; perioperative uses of dexamethasone; comparison between cortisol and dexamethasone negative feed-back action in humans; the effect of dexamethasone on parathyroid hormone-related protein expression by oral cancer cells; and the effects of dexamethasone on the proliferation and differentiation of osteoblasts.

Table of Contents:

Preface; Dexamethasone in the Treatment of Meconium Aspiration Syndrome: Benefits versus Side Effects; Dexamethasone Effects in Hyperinfection Syndrome Due to Strongyloidiasis; Dexamethasone's Uses in Retinal Diseases; Anti-Tumor Activities of Dexamethasone; Perioperative Uses of Dexamethasone; Comparison between Cortisol's & Dexamethasone's Negative Feedback Action in Humans: Evidence for Preferential Sensitivity to the Natural Glucocorticoid; Effect of Dexamethasone on Parathyroid Hormone-related Protein Expression by Oral Cancer Cells; The Effects of Dexamethasone on the Proliferation & Differentiation of the Osteoblasts.