Myopathies: New Research

Description:

Myopathies are a clinically and genetically heterogenous group of muscle diseases characterized by pathologic changes in muscle fibers that compromise their contractile ability. The authors of this book have gathered new research from across the globe and topics discussed in this compilation include inherited myopathies with distinct clinical manifestations; muscle biopsy as a diagnostic procedure in suspected myopathies; inflammation in dysferlinopathies; mitochondrial disorders; dysphagia in the myopathies; and aB-Crystallin (HSPB5) and myofibrillar
myopathies. (Imprint: Nova Biomedical)

Contents

Chapter 1 - Inherited Myopathies (pp. 1-40)
Authors / Editors: (Ildikó Kelemen-Valkony, Márton Kiss, Katalin Csiszár, Mátyás Mink, Department of Genetics, University of Szeged, Középfasor, Szeged, Hungary, and others)

Chapter 2 - New Vistas in Understanding the Pathophysiology of Valosin-Containing Protein (VCP)/p97 Disease (pp. 41-56)
Authors / Editors: (Virginia E. Kimonis, Angèle Nalbandian, Katrina Llewellyn, Manaswitha Khare, Eric Dec, Marie Wencel, Hong Yin, Vincent Caiozzo, Barbara Martin, Charles Smith, Syed Rafi, Annabel Wang, Tahseen Mozaffar, John Weiss, Division of Genetics and Metabolism, Department of Pediatrics, Department of Neurology, University of California Irvine, California, and others)

Chapter 3 - Muscle Biopsy: Diagnostic Value in Suspected Myopathies (pp. 57-74)
Authors / Editors: (Endre Pál, Emese Lovadi, István Gáti, Hajnalka Merkli, Sámuel Komoly,Department of Neurology, University of Pécs, Pécs, Hungary)

Chapter 4 - Inflammation in Dysferlinopathies: What Can we Learn from Animal Models? (pp. 75-88)
Authors / Editors: (Marija Meznaric, University of Ljubljana, Medical Faculty, Institute of Anatomy, Ljubljana, Slovenia)

Chapter 5 - The ABC of Mitochondrial Disorders (pp. 89-98)
Authors / Editors: (Daniele Orsucci, Michelangelo Mancuso, Lucia Petrozzi, Costanza Simoncini, Elena Caldarazzo Ienco, Gabriele Siciliano, Department of Neuroscience, Neurological Clinic, University of Pisa, Italy)

Chapter 6 - Dysphagia in the Myopathies (pp. 99-114)
Authors / Editors: (Danielle Ramos Domenis, Raphaela Barroso Guedes Granzotti, Paula de Carvalho Macedo Issa Okubo, Claudia Ferreira da Rosa Sobreira, Roberto Oliveira Dantas, Department of Ophthalmology, Otolaryngology and Head and Neck Surgery, University Hospital of Ribeirao Preto, SP, Brazil, and others)

Chapter 7 - alphaB-Crystallin (HSPB5) and Myofibrillar Myopathies (pp. 115-138)
Authors / Editors: (Isidre Ferrer, Dolores Moreno, Anna Janue, Institut de Neuropatologia, Servei Anatomia Patologica, IDIBELL-Hospital Universitari de Bellvitge, Universitat de Barcelona, Hospitalet de Llobregat, CIBERNED, Spain)

Editors: Howard S. Washington and Chris E. Castillo Jimenez