Parkinson's Disease: Diagnosis, Treatment and Prognosis

Description:

Parkinson's disease (PD) is the second most common neurodegenerative disorder and is caused by degeneration and dysfunction of dopaminergic neurons in substantia nigra. The disease usually clinically starts at age 54-60 and the mean duration from diagnosis to death is about 15 years. In this book, the authors study the diagnosis, treatment and prognosis of Parkinson's disease. Topics include palliative care in Parkinson's disease; therapeutic interventions based on the modulation of cellular degradative systems in Parkinson's physiopathology; Parkinson's disease related changes of oscillatory activity in discrimination tasks; Deep Brain Stimulation (DBS) and Parkinson's disease; and the genetic aspects for diagnosis of Parkinson's disease in different populations. (Imprint: Nova Biomedical)

Table of Contents:

Chapter 1 - Therapeutic Intervention at Cellular Clearance Mechanisms: Significance to Parkinson’s Disease (pp. 1-34)
Authors / Editors: (Daniela M. Arduino, A. Raquel Esteves, Diogo Martins-Branco, Daniel Santos, Diana F.F. Silva, Sandra M. Cardoso, CNC–Center for Neuroscience and Cell Biology, University of Coimbra, Faculty of Medicine, University of Coimbra, Coimbra, Portugal)

Chapter 2 - Parkinson’s Disease Related Changes of Oscillatory Activity in Discrimination Tasks (pp. 35-66)
Authors / Editors: (Juliana Dushanova, Institute of Neurobiology, Bulgarian Academy of Sciences, Bulgaria)

Chapter 3 - New Insights into the Mechanism of Slowing of Voluntary Movements in Parkinson’s Disease (pp. 67-98)
Authors / Editors: (Tateo Warabi, Kikuro Fukushima, Peter M. Olley, Clinical Brain Research Laboratory, Department of Neurology, Sapporo Yamanoue Hospital, Sapporo, Japan)

Chapter 4 - The Relevance of the Neural Code in the Basal Ganglia for the Treatment of Parkinson’s Disease: Beyond the Rate and Pattern Models - Implications for the Understanding and Application of DBS (pp. 99-120)
Authors / Editors: (Daniela Andres, Daniel Cerquetti, Marcelo Merello, Movements Disorders Section, Raul Carrea Institute for Neurological Research, Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI), Argentina, and others)

Chapter 5 - Genetic Aspects for Diagnosis of Parkinson’s Disease in Different Populations (pp. 121-146)
Authors / Editors: (Myeong-Sang Cheon, Lilian Chan, Dennis Cordato, Daniel Kam Yin Chan, Department of Aged Care & Rehabilitation, University of New South Wales, Bankstown Hospital Bankstown, Australia, and others)

Chapter 6 - Role of Executive Dysfunction in the Unawareness of Dyskinetic Movements (pp. 147-164)
Authors / Editors: (Sara Palermo, Martina Amanzio, Department of Psychology, University of Turin, Turin, Italy)

Chapter 7 - Treatment of Parkinson’s Disease and Parkinsonism in the Elderly (pp. 165-178)
Authors / Editors: (Fulvio Lauretani, Marcello Maggio, Anna Nardelli, Gian Paolo Ceda, Geriatric Unit and Laboratory of Movement Analysis, Geriatric and Rehabilitation Department, University Hospital of Parma, Parma, Italy, and others)

Chapter 8 - Gait Velocity, Attention and Exercise in Parkinson’s Disease (pp. 179-190)
Authors / Editors: (Lilian Teresa BuckenGobbi, Rodrigo Vitório, Claudia Teixeira-Arroyo, Ellen Lirani-Silva, Natalia Madalena Rinaldi, Fabio Augusto Barbieri, Marcelo Pinto Pereira, Paulo Cezar Rocha Santos, Rosangela Alice Batistela,PROPARKI Group, São Paulo State University, UNESP, Brazil)

Chapter 9 - Palliative Care in Parkinson’s Disease (pp. 191-200)
Authors / Editors: (Johan Lökk, Dept of Neurobiology, Care Sciences, and Society, Karolinska Institutet; Karolinska University Hospital, Stockholm, Sweden)

Chapter 10 - Relationship between Dysphagia and Depressive States in Patients with Parkinson's Disease (pp. 201-208)
Authors / Editors: (Meng Han, Hirofumi Ohnishi, Michio Nonaka, Rika Yamauchi, Takayoshi Hozuki, Takashi Hayashi, Masaki Saitoh, Shin Hisahara, Tomihiro Imai, Shun Shimohama, Mitsuru Mori, Department of Hygiene, Yamaguchi University School of Medicine, Yamaguchi, Japan, and others)

Chapter 11 - Neuroprotective Effects of the Methanolic Extract of Hibiscus Asper Leaves against a 6-Hydroxydopamine-Induced Rodent Model of Parkinson’s Disease (pp. 209-216)
Authors / Editors: (L. Hritcu, H.S. Foyet, Department of Biology, Alexandru Ioan Cuza University, Iasi, Romania, and others)

Chapter 12 - Constipation with Low Myocardial Metaiodobenzylguanidine Uptake are the Initial Features of Parkinson’s Disease (pp. 217-222)
Authors / Editors: (Ryuji Sakakibara, Yohei Tsuyuzaki, Fuyuki Tateno, Masahiko Kishi, Tomoyuki Uchiyama, Tatsuya Yamamoto, Neurology, Internal Medicine, SakuraMedicalCenter, TohoUniversity, Sakura, Japan, and others)