Molecular Imaging in the Clinical Neurosciences (Neuromethods, Vol. 71)

Description

• Provides readers with up-to-date information on the basic principles of molecular imaging and its major applications in clinical neuroscience
• Features a section on psychiatry and neurology
• Includes key tips and expert guidance to ensure successful research results

While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function. In Molecular Imaging in the Clinical Neurosciences, experts in the field provide the reader with up-to-date information on the basic principles of molecular imaging and its major applications in the clinical neurosciences. Beginning with a section offering a comprehensive review of the methodological foundations from physics, chemistry, and mathematics including mathematical modeling, essential for meaningful data analysis, this detailed volume then continues with sections on the major biological principles and neurochemical targets relevant in current neuroimaging research and the major clinical applications from the fields of psychiatry and neurology. Written for the popular Neuromethods series, this work contains the kind of key description and implementation advice that guarantees successful results.

Authoritative and cutting-edge, Molecular Imaging in the Clinical Neurosciences serves as a helpful source of knowledge for both basic and clinical scientists from psychology, psychiatry, neurology, nuclear medicine, nuclear chemistry, and the associated disciplines, all of which makes molecular imaging such a rewarding, interdisciplinary field of work.

Content Level » Professional/practitioner
Keywords » Clinical neurosciences - Functional imaging techniques - Molecular imaging - Neuroimaging research - Positron Emission Tomography - Single Photon Emission Computed Tomography
Related subjects » Neurology - Neuroscience

TABLE OF CONTENTS

1. Instrumentation and Physical Principles
   Christoph Weirich and Hans Herzog
2. Molecular Neuroscience and the Quantification of Brain Dynamics
   Albert Gjedde and Dean F. Wong
3. Radiopharmaceutical Chemistry
   Markus Piel and Frank Rösch
4. Introduction to the Basics of Magnetic Resonance Imaging
   Klaus Möllenhoff, Ana-Maria Oros-Peusquens, and N. Jon Shah
5. Quantification of Cerebral Blood Flow
   Adriaan A. Lammertsma
6. The Assay of Enzyme Activity by Positron Emission Tomography
   Paul Cumming and Neil Vasdev
7. Molecular Imaging Studies of Second Messenger Pathways: Looking Deeper than the Membrane
   Paul Cumming and Neil Vasdev
8. Quantification of Neuroreceptors and Neurotransporters
   Hiroshi Ito, Mika Naganawa, Chie Seki, Harumasa Takano, Iwao Kanno, and Tetsuya Suhara
9. Measuring Dopamine Synaptic Transmission with Molecular Imaging and Pharmacological Challenges: The State of the Art
   Marc Laruelle
10. Small Animal Imaging with Positron Emission Tomography (PET)
    Hideo Tsukada
11. Emission Imaging in Dementia
    Julie C. Price, Brian J. Lopresti, and Victor L. Villemagne
12. Neurochemical Imaging of Addictive Disorders
    Allegra Broft and Diana Martinez
13. Molecular Imaging of Mood Disorders
    Jeffrey H. Meyer
14. Molecular Imaging in Schizophrenia
    Oliver Howes
15. Imaging the Pathophysiology of Ischemic Cerebrovascular Disease
    Wolf-Dieter Heiss
16. Molecular Imaging of Brain Tumors
    Karl-Josef Langen
17. Molecular Imaging in Parkinson’s Disease
    Laura K. Teune and Karl L. Leenders
18. Epilepsy
    Alexander Hammers