Biotargets of Cancer in Current Clinical Practice

ABOUT THIS BOOK

• Provides the latest information on the validation status of each novel biomarker
• Covers the present debate on potential clinical use of newly discovered biochemical markers and on patentability of genetic information
• Chapter authors are experts on the particular cancer type

Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.

Content Level » Professional/practitioner
Keywords » Cancer Therapeutics - Epidemiology - Metastasis
Related subjects » Biomedical Sciences - Oncology & Hematology - Pathology

TABLE OF CONTENTS

• Ch. 1- Central Nervous System Tumors Paolo Aloisi , Francesco Martella, Davide Cerone, Giampiero Porzio
• Ch. 2- Head and Neck Tumors
• Keith D. Hunter, Robert Bolt
• Ch. 3- Thyroid Cancer Laura D. Locati , Angela Greco, Maria Grazia Borrello , Maria Luisa Carcangiu, Paolo Bossi , Roberta Granata , Lisa Licitra
• Ch. 4- Targeted Therapies for Non-Small Cell Lung Cancer Giulio Metro, Lucio Crinò
• Ch. 5- Non-Hodgkin Lymphomas Roberta Zappasodi, Massimo Di Nicola
• Ch. 6- Leukemias Lia Ginaldi , Massimo De Martinis
• Ch. 7- Breast Cancer Nadia Rucci, Luca Ventura, Anna Teti
• Ch. 8- Esophago-Gastric Cancer Alex M. Reece-Smith, Simon L. Parsons , Sue A. Watson
• Ch. 9- Colorectal Cancer David Church, Rachel Midgley, David Kerr
• Ch. 10- Hepatocellular Carcinoma Yasunori Minami , Masatoshi Kudo
• Ch. 11- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma Laura S. Schmidt
• Ch. 12- Bladder Cancer Andrea Tubaro, Daniele Santini, Cosimo De Nunzio, Alice Zoccoli, Michele Iuliano
• Ch. 13- Biomarkers in Prostate cancer Mauro Bologna, Carlo Vicentini
• Ch. 14- Ovarian Cancer Jessica Wangui Oribabor , Allison Ambrosio , Cesar M. Castro, Michael J. Birrer
• Ch. 15- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer Annekathryn Goodman, Leslie S. Bradford, Leslie A. Garrett
• Ch. 16- Biotargets in Sarcomas: The Past, Present and a Look into the Future Vivek Subbiah, Razelle Kurzrock
• Ch. 17- Melanoma and other skin cancers Kim H.T. Paraiso, Jobin K. John, Keiran S.M. Smalley
• Ch. 18- Molecular pathology of cancer metastasis: suggestions for future therapy Adriano Angelucci, Edoardo Alesse
• Ch. 19- Current and future developments in cancer therapy research: miRNAs as new promising targets or tools Marilena V. Iorio, Patrizia Casalini, Claudia Piovan, Luca Braccioli, Elda Tagliabue