Stem Cell, Regenerative Medicine and Cancer - Cell Biology Research Progress

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Description:

Of the estimated trillion cells that build up our bodies, only a little number can self-renew and give rise to many different cell types. These unspecialized cells are called stem cells. Stem cell division and differentiation is fundamental to the development of the mature organism. Stem cells have recently attracted significant attention largely due to their potential medical benefits in the fields of therapeutic cloning and regenerative medicine. Because stem cells can become many specialized types of cells of the organs, they have the potential to treat many diseases, including Alzheimer's disease, Parkinson's disease, type-1 diabetes, spinal cord injury, stroke, burns, heart disease, osteoarthritis, and rheumatoid arthritis. This book focuses on the application of stem cells in regeneration and repair of the organs in disease and aging.

Table of Contents:

• Chapter 1 - Epigenetic modifications in reprogramming and lineage specifications from embryonic stem cells: current trends and relevance in developing regenerative medicine pp. 3-30
  Authors / Editors: (Jinnuo Han, Henry Chung, Perminder S Sachdev and Kuldip S Sidhu)
• Chapter 2 - Regenerative medicine: lessons from planarians pp. 31-70
  Authors / Editors: (Francesc Cebrià, Teresa Adell and Emili Saló)
• Chapter 3 - Mesenchymal stem cells in tissue regeneration and organogenesis using porcine model pp. 71-118
  Authors / Editors: (B. Mohana Kumar and Gyu Jin Rho)
• Chapter 4 - Retinal stem cells, signaling and regeneration pp. 119-140
  Authors / Editors: (Fumi Kubo)
• Chapter 5 - A pathophysiological view of the neural stem cell niche pp. 141-156
  Authors / Editors: (Ricardo Pardal and Aida Platero-Luengo)
• Chapter 6 - Adult stem and trans-amplifying cells in repair through granulation tissue: role of the pericytic vasculature niche pp. 157-186
  Authors / Editors: (Lucio Díaz-Flores, Ricardo Gutiérrez, Juan F. Madrid, et al.)
• Chapter 7 - Stem cells in tooth development and regeneration pp. 187-208
  Authors / Editors: (Masaki J. Honda and Hayato Ohshima)
• Chapter 8 - Role of Stem cells in lung injury pp. 209-230
  Authors / Editors: (Ana L. Mora and Mauricio Rojas)
• Chapter 9 - Gene modification and stem cell transplantation for regenerating the mammalian inner ear: A new approach in the treatment of sensorineural hearing loss pp. 231-280
  Authors / Editors: (Petros V. Vlastarakos, and Thomas P. Nikolopoulos)
• Chapter 10 - Putative stem cells in mucosas of the esophago-gastrointestinal tract pp. 281-310
  Authors / Editors: (C. A. Rubio)
• Chapter 11 - Stem and progenitor cells in muscle regeneration and potential treatment pp. 311-348
  Authors / Editors: (Anna Burdzińska)
• Chapter 12 - Stem cells in kidney regeneration and cancer pp. 349-368
  Authors / Editors: (Shree Ram Singh)
• Chapter 13 - Stem cell treatment for complicated diabetes pp. 369-398
  Authors / Editors: (Jong Yoon Bahk, Jae Hun Jung, Seung Ki Min and Hoon Han)
• Chapter 14 - Deterioration of hematopoietic stem cells with aging pp. 399-426
  Authors / Editors: (MiJung Kim, Seung Ah Kim, Chan Jeoung Park, et al.)
• Chapter 15 - MicroRNAs in skin morphogenesis and diseases pp. 427-440
  Authors / Editors: (Damjan Glavač)
• Chapter 16 - Effect of cellular microenvironment and paracrine signals on chondrogenic differentiation of mesenchymal progenitor cells pp. 441-466
  Authors / Editors: (Susanne Grässel and Rita Dreier)
• Chapter 17 - Hypoxia-inducible factor, osteogenesis and chondrogenesis pp. 467-476
  Authors / Editors: (Yiyong Wei and Xiaotang Sun)
• Chapter 18 - Nanotechnology in the stem cells research and development: imaging and therapies for injuries and degenerative diseases pp. 477-514
  Authors / Editors: (Jiajia Ji and Daxiang Cui)
• Chapter 19 - Cancer stem cells: light and shadows pp. 515-528
  Authors / Editors: (Caterina AM La Porta)
• Chapter 20 - Stem Cells in Head and Neck cancer: a key to the future? pp. 529-536
  Authors / Editors: (Chiara Bianchini, Andrea Ciorba, Roberta Piva)
• Chapter 21 - Stem Cell and Oral Squamous Cell Carcinoma Tumorigenesis pp. 537-576
  Authors / Editors: (Wan-tao Chen, Zhi-yuan Zhang, Ping Zhang, et al.)
• Chapter 22 - Mammary epithelial and breast cancer stem cells pp. 577-604
  Authors / Editors: (Brian J. Morrison, Brent A. Reynolds, Chris W. Schmidt, and J. Alejandro Lopez)
• Chapter 23 - Stem cells and breast cancer pp. 605-622
  Authors / Editors: (Benedetta Bussolati, Cristina Grange, Anna Sapino and Giovanni Camussi)
• Chapter 24 - Notch signaling in cancer, stem cells and cancer stem cells pp. 623-642
  Authors / Editors: (Jeevisha Bajaj, Deepa Subramanyam and Sudhir Krishna)
• Chapter 25 - Epithelial-to-mesenchymal transition, stem cells, and cancer progression pp. 643-666
  Authors / Editors: (Joseph H. Taube and Sendurai A. Mani)
• Chapter 26 - Cancer stem cells in prostate adenocarcinoma pp. 667-694
  Authors / Editors: (Daniela Fioriti, Anna Bellizzi, Franco Di Silverio, et al.)
• Chapter 27 - Heat shock proteins in normal and cancer stem cell biology: implications for regenerative and chemotherapeutic medicine pp. 695-716
  Authors / Editors: (Earl Prinsloo, Leanne C. Cooper, Buhle Moyo, et al.)
• Chapter 28 - Human embryonic stem cell platforms in drug screening and predictive toxicology pp. 717-736
  Authors / Editors: (Kaushik Dilip Deb)