Hepatitis C and Liver Transplantation

Description:

This book provides a single reference for all transplant professionals involved in the care of HCV patients who have unique problems not encountered in other liver transplant patients. In the liver transplant community, it is well-known that decompensated cirrhosis from hepatitis C virus (HCV) is the leading indication for orthotopic liver transplantation (OLT) in the United States and most Western countries. Short-term results which initially seemed promising and comparable to other carefully selected liver transplant recipients now appear less encouraging with cirrhosis developing in 10-25% of patients by 5 years. Despite these concerns, there is an increased amount of data which supports re-transplantation in carefully selected patients.

Editors: Sandeep Mukherjee (University of Nebraska Medical Center, Omaha, NE, USA)

Table of Contents:

Preface

Part I

• Chapter 1. Epidemiology and burden of hepatitis C in the United States;pp. 1-11
  (Miriam J. Alter, University of Texas Medical Branch, Galveston, Texas, USA)
• Chapter 2. State of the art treatment of Hepatitis C;pp. 13-27
  (Hans L. Tilmann, Alex Thompson, Keyur Patel, Duke University, Durham, North Carolina, USA)
• Chapter 3. Beyond interferon and ribavirin-novel antiviral therapies for chronic Hepatitis C;pp. 29-44
  (Rudolf E. Stauber, Medical University of Graz, Austria)
• Chapter 4. Antiviral therapy for decompensated Hepatitis C-related cirrhosis before liver transplantation;pp. 45-53
  (Bruno Roche, Didier Samuel, Univ Paris-Sud, Villejuif, France)

Part II

• Chapter 5. Impact of preservation injury and donor factors on Hepatitis C recurrence after liver transplantation;pp. 57-76
  (Stephen C Rayhill, Oregon Health Sciences University, Oregon, Portland, Oregon, USA)

PART III

• Chapter 6. The natural history of recurrent Hepatitis C following liver transplantation;pp. 79-96
  (Ed Gane, Auckland Hospital, Auckland, New Zealand)
• Chapter 7. Mechanisms of liver injury from recurrent Hepatitis C;pp. 97-114
  (Ulrich Spengler, Jacob Nattermann, University of Bonn, Bonn, Germany
• Chapter 8. Hepatitis C and living donor liver transplantation;pp. 115-125
  (Alexander Kuo, University of California San Diego, San Diego, California, USA and Norah A. Terrault, University of California San Francisco, San Francisco, California, USA)
• Chapter 9. A logical approach to the use of immunosuppression in liver transplantation for hepatitis C virus;pp. 127-137
  (James Neuberger, Queen Elizabeth Hospital, Birmingham, England)
• Chapter 10. Differentiation of recurrent Hepatitis C virus from hepatic allograft rejection;pp. 139-153
  (Lisa R. Dixon, Roniel Cabrera, University of Florida, Gainesville, Florida, USA)
• Chapter 11. Monitoring hepatic fibrosis from Hepatitis C recurrence after liver transplantation;pp. 155-168
  (Marina Berenguer, University of Valencia, Valencia, Spain)
• Chapter 12. A systematic review of prophylactic anti-viral therapy for patients undergoing liver transplantation for chronic Hepatitis C;pp. 169-182
  (Kurinchi S. Gurusamy, Andrew K. Burroughs, Brian R. Davidson, Royal Free Hospital and University College School of Medicine, London, England)
• Chapter 13. A systematic review of anti-viral therapy for recurrent Hepatitis C after liver transplantation;pp. 183-200
  (Kurinchi S. Gurusamy, Andrew K. Burroughs, Brian R. Davidson)
• Chapter 14. Hepatitis C and liver retransplantation;pp. 201-216
  (Hanna Kraus, Lisa Forman, University of Colorado Health Sciences Center, Denver, Colorado, USA)
• Chapter 15. Evaluation and outcomes of liver transplantation for Hepatitis and HIV co-infection;pp. 217-228
  (Ishfaq Bhat, Sandeep Mukherjee, University of Nebraska Medical Center, Omaha, Nebraska, USA)
• Chapter 16. Quality of life after liver transplantation for Hepatitis C;pp. 229-244
  (Jillian B. Kallman, Zobair M. Younossi, Nova Fairfax Hospital, Virginia, USA)
• Chapter 17. Pediatric liver transplantation for Hepatitis C;pp. 245-259
  (Jacfranz J. Guiteau, Ronald T. Cotton, Saul J. Karpen, Christine A. O’Mahony, John A. Goss, Baylor College of Medicine, Houston, Texas, USA)

Index