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Suppression and Regulation of Immune Responses. Methods and Protocols (Methods in Molecular Biology, Vol. 677)
Cuturi, Mª.C. — Anegon, I.
1ª Edición Octubre 2010
Inglés
Tapa dura
473 pags
1300 gr
18 x 26 x 3 cm
ISBN 9781607618683
Editorial HUMANA PRESS
About this book
Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.
Content Level » Professional/practitioner
Keywords » Immunoregulation - Molecular mechanisms - Physiopathological
situations - Regulatory cells - Suppressive molecules - T-cells - Therapeutic
applications
Related subjects » Immunology
Table of contents
Part I: Regulatory Cells 1. Natural and Induced T CD4+CD25+FOXP3+ Regulatory
T Cells Lucienne Chatenoud 2. Polyclonal Expansion of Human CD4+CD25+ Regulatory
T Cells Petra Hoffmann, Ruediger Eder, and Matthias Edinger 3. Methods for In
vitro Generation of Human Type 1 Regulatory T (Tr1) Cells Silvia Gregori, Maria
Grazia Roncarolo, and Rosa Bacchetta 4. Ex vivo Generation of Regulatory T-Cells:
Characterization and Therapeutic Evaluation in a Model of Chronic Colitis Fridrik
Karlsson, Sherry Jackson, Laura Gray, Songlin Zhang, and Matthew B. Grisham
5. Phenotypic and Functional Characterization of CD8+ T Regulatory Cells Séverine
Ménoret, Carole Guillonneau, Séverine Bezié, Lise Caron,
Ignacio Anegon, and Xian-Liang Li 6. Regulatory CD4- CD8- Double Negative T
Cells Edward Y. Kim, Stephen C. Juvet, and Li Zhang 7. Identifying Regulatory
B Cells (B10 Cells) that Produce IL-10 in Mice Takashi Matsushita and Thomas
F. Tedder 8. DCs in Immune Tolerance in Steady-State Conditions Tomohiro Fukaya,
Hideaki Takagi, Honami Taya, and Katsuaki Sato 9. Plasmacytoid Dendritic Cells
in Tolerance Eric Gehrie, William Van der Touw, Jonathan S. Bromberg, and Jordi
C. Ochando 10. In vitro Generated DC with Tolerogenic Functions: Perspectives
for In vivo Cellular Therapy Cees van Kooten and Kyra A. Gelderman 11. Preparation
of Mouse Bone Marrow-Derived Dendritic Cells with Immunoregulatory Properties
Mercedes Segovia, Maria Cristina Cuturi, and Marcelo Hill 12. Myeloid Derived
Suppressor Cells (MDSC): Characterization and Expansion in Models of Endotoxemia
and Transplantation Nicolas Van Rompaey and Alain Le Moine 13. Human Regulatory
Macrophages James A. Hutchinson, Paloma Riquelme, Edward K. Geissler, and Fred
Fändrich 14. NKT and Tolerance Julien Diana, Lucie Beaudoin, Anne-Sophie
Gautron, and Agnès Lehuen 15. Anti-Inflammatory and Immunosuppressive
Functions of Mast Cells Janet Kalesnikoff and Stephen J. Galli 16. A Mesenchymal
Stem Cell Potency Assay Joy Jiao, Jack M. Milwid, Martin L. Yarmush, and Biju
Parekkadan 17. In Vitro Analyses of the Immunosuppressive Properties of Neural
Stem/Progenitor Cells Using Anti-CD3/CD28 Activated T Cells Virginie Bonnamain,
Isabelle Neveu, and Philippe Naveilhan Part II: Regulatory Molecules 18. Immunoregulatory
Properties of Heme Oxygenase-1 Philippe Blancou, Virginie Tardif, Thomas Simon,
Séverine Rémy, Leandro Carreño, Alexis Kalergis, and Ignacio
Anegon 19. Indoleamine, 2,3-Dioxygenase, and Regulatory Function: Tryptophan
Starvation and Beyond Ciriana Orabona and Ursula Grohmann 20. Regulatory T Cell
Enrichment by IFN-? Conditioning Gang Feng, Kathryn J. Wood, and Andrew Bushell
21. Transforming Growth Factor-Beta: Recent Advances on Its Role in Immune Tolerance
Pierre-Yves Mantel and Carsten B. Schmidt-Weber 22. Induction of Tolerogenic
Dendritic Cells by NF-?B Blockade and Fc? Receptor Modulation Leandro J. Carreño,
Claudia A. Riedel, and Alexis M. Kalergis 23. Fine-Tuning Antitumor Responses
through the Control of Galectin-Glycan Interactions: An Overview Mariana Salatino
and Gabriel A. Rabinovich 24. Regulation of Lymphocytes by Nitric Oxide Christian
Bogdan Part III: Physiopathological Situations 25. Pregnancy: Tolerance and
Suppression of Immune Responses Ana Claudia Zenclussen, Anne Schumacher, Maria
Laura Zenclussen, Ana Teles, Nadja Brachwitz, Pablo Casalis, Tarek El-Mousleh,
Federico Jensen, and Katja Woidacki 26. Organ Transplantation: Modulation of
T Cell Activation Pathways Initiated by Cell Surface Receptors to Suppress Graft
Rejection Kathleen Weatherly and Michel Y. Braun 27. Immunosuppressive Mechanisms
During Viral Infectious Diseases Ghanashyam Sarikonda and Matthias G. von Herrath
28. Ocular Immune Privilege Sites Sharmila Masli and Jose L. Vega 29. Immunoprivileged
Sites: The Testis Monika Fijak, Sudhanshu Bhushan, and Andreas Meinhardt
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