Deep Brain Stimulation. Applications, Complications and Side Effects

Book Description:

In neurotechnology, deep brain stimulation (DBS) refers to a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain. DBS in select brain regions has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders such as chronic pain, Parkinson’s disease, tremor and dystonia. Despite the long history of DBS, its underlying principles and mechanisms are still not clear. While DBS has proven helpful for some patients, there is potential for serious complications and side effects. This book presents current research on this cutting edge treatment. Success of functional stereotactic procedures is shown to depend on a variety of factors, including patient selection, methodology of choice and localization of the target, and the experience of the neurosurgery team. Complications on the use of the procedure in the treatment of Parkinson’s Disease are also presented. The use of Vagus nerve stimulation on treatment-resistant patients with major depression is discussed as well.

Table of Contents:

Preface

*Common Questions and Answers to Deep Brain Stimulation Surgery;pp. 1-29
(Fernando Seijo, Beatriz Lozano, Elena Santamarta Functional Neurosurgery Unit, Neurosurgery Department, Hospital Universitario Central deAsturias, Oviedo, Spain, and others)

*Deep Brain Stimulation and Cortical Stimulation Methods: A Commentary on Established Applications and Expected Developments;pp. 31-47
(Damianos E. Sakas, Ioanis G. Panourias, Department of Neurosurgery, University of Athens Medical School, Evangelismos Hospital, Athens, Greece)

*Cortical stimulation versus deep brain stimulation in neurological and psychiatric disorders. Current state and future prospects;pp. 49-82
(Damianos E. Sakas, Ioannis G. Panourias)

*Invasive cortical stimulation for Parkinson’s disease and movement disorders;pp. 83-97
(B. Cioni, A.R. Bentivoglio, C. De Simone, A. Fasano, C. Piano, D. Policicchio, V. Perotti, M. Meglio)

*Deep Brain Stimulation in Epilepsy: Experimental and Clinical Data;pp. 99-117
(Colin Deransart et al., Université Joseph Fourier, France)

*Psychosurgery of Obsessive-Compulsive Disorder: A new Indication for Deep Brain Stimulation?;pp. 119-132
(Bruno Aouizerate et al., Université Victor Segalen Bordeaux, France)

*Deep Brain Stimulation in Adult and Pediatric Dystonia;pp. 133-144
(Laura Cif et al., Montpellier University Hospital, France)

*Deep Brain Stimulation Of the Subthalamus: Neuropsychological Effects;pp. 145-161
(R. Moretti, P. Torre, R. M. Antonello, A.Bava)

*Subthalamic High-frequency Deep Brain Stimulation Evaluated by Positron Emission Tomography in a Porcine Parkinson Model;pp. 163-176
(Mette S. Nielsen, Carsten R. Bjarkam, Flemming Andersen, Paul Cumming, Arne Møller, Jens. C. Sørensen, Department of Neurobiology, Institute of Anatomy, University of Aarhus, Denmark and others)

*Current and Future Perspectives on Vagus Nerve Stimulation in Treatment-Resistant Depression;pp. 177-188
(Bernardo Dell'Osso, Giulia Camuri, Lucio Oldani, Department of Psychiatry, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy)

Index

Editors: Mark H. Rogers and Paul B. Anderson