Drug Toxicity. New Research

Description

The systemic effects of a drug are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patient's body to eliminate the drug. This new book presents recent and important research in the field.

Table of contents

Preface

Chapter 1 - Drug Toxicity Research Trends; pp. 1-28
(Sarabjeet Singh, Department of Medicine, Chicago Medical School at Rosalind Franklin, University of Medicine and Sciences, Chicago, Sanjeev Wasson, Cleveland Clinic Foundation, Cleveland, OH)

Chapter 2 - Antipsychotic drugs: A critical review focusing on adverse event profile; pp. 29-51
(Francisco José Álvarez, Neurology Department, Hospital San Juan de Dios, Spain)

Chapter 3 - A Critical Approach to an Allergic Paradox: Allergic and Allergic-Like Reactions to Glucocorticoids. Delayed Hypersensitivity Mechanisms; pp. 53-72
(M.T. Ventura, R. Buquicchio, Department of Internal Medicine, Immunology and Infectious Diseases (MIDIM), University of Bari Medical School, Italy, G.F. Calogiuri, Division Pneumologic Hospital A. Galateo-San Cesario di Lecce, Italy, et al.)

Chapter 4 - Practical Hemodynamic Profiles of Valvular, Restrictive and Constrictive Pericardial Diseases; pp. 73-88
(Sanjeev Wasson, Department of Cardiology, Cardiac Electrophysiology, Cleveland Clinic Foundation, Hanumanth K. Reddy, Department of Cardiology, Cardiac Electrophysiology, Medical Center of South Arkansas)

Chapter 5 - Rapid Efficacy and Lethal Toxicity of the Artemisinin Derivatives Related to Drug Pharmacokinetic Profiles in Humans and in Animal Species; pp. 89-187
(Qigui Li, Wilbur K. Milhous, Peter J. Weina, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, USA)

Chapter 6 - Nephrotoxicity of Nonsteroidal Anti-Inflammatory Drugs: Focus on Selective Cyclooxygenase-2 (COX-2) Inhibitors; pp. 187-222
(Steven G. Coca and Mark A. Perazella, Yale University School of Medicine, CT)

Chapter 7 - Ethanol Induced Adaptive Changes in Structure and Function of NMDA Receptors; pp. 223-261
(Jozef Nagy, Sándor Kolok, András Boros, et al., Gedeon Richter Ltd., Pharmacological and Drug Safety Research, Laboratory of Molecular and Cellular Biology, Hungary)

Chapter 8 - Antihormonal Agents in the Citotoxicity Increase of Anticancer Drugs in Cervical Cancer; pp. 263-290
(P. García-López and R. Jurado, Instituto Nacional de Cancerología, Mexico)

Chapter 9 - Influence of Low-toxicity Chemical Agents at Low Doses on Oxidative Processes in the Liver of Mice; pp. 291-299
(M.V. Kozlov, V.V. Urnysheva, L.N. Shishkina, N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Russia)

Chapter 10 - Nephrotoxicity of D-Serine in Rats; pp. 301-304
(Ryuichi Konno, Department of Microbiology, Dokkyo Medical University, Japan)

Index